Biermann, Niklas and Eschenbacher, Elisabeth and Brebant, Vanessa and Heinicke, Norbert and Brix, Eva and Prantl, Lukas and Anker, Alexandra M. (2024) Patient characteristics may affect the lymphatic staining ability of Indocyanine green and Patent blue during lymphaticovenous anastomosis. CLINICAL HEMORHEOLOGY AND MICROCIRCULATION, 86 (1-2). pp. 153-158. ISSN 1386-0291, 1875-8622
Full text not available from this repository. (Request a copy)Abstract
BACKGROUND: The use of dyes like Indocyanine green (ICG) and Patent blue facilitates the identification of lymphatic vessels during lymphaticovenous anastomosis (LVA) surgery. However, some patients experience "staining failure". In these cases, no stained lymphatic vessels can be detected, making supermicrosurgical LVA even more complex. OBJECTIVE: This study aims to investigate patient-related factors that may interfere with lymphatic vessel staining during LVA. METHODS: A retrospective study was conducted on 30 patient charts, focusing on patient characteristics and the staining quality of ICG and Patent blue dye. Statistical analyses were performed to identify correlations between variables. RESULTS: Significant correlations were found between higher age and secondary lymphedema, longer duration of lymphedema in male patients until surgery and reoccurring cellulitis and Patent blue staining. Notably, recurrent infections to the lymphatic system resulted in inferior staining ability during LVA surgery. CONCLUSIONS: Due to staining failure the detection of functional lymphatic vessels remains challenging in LVA surgery. A more extensive preoperative workup is recommended for patients with recurrent cellulitis to optimize surgical feasibility and procedure quality in LVA treatment for lymphedema.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | LOWER-EXTREMITY LYMPHEDEMA; CELLULITIS; SYSTEM; DYE; Lymphedema; lymphedema surgery; lymphaticovenous anastomosis; lymphaticovenous bypass; LVA; Indocyanine green; Patent blue dye; blue dye; lymphography |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Plastische-, Hand- und Wiederherstellungschirurgie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 28 Jul 2025 12:17 |
| Last Modified: | 28 Jul 2025 12:17 |
| URI: | https://pred.uni-regensburg.de/id/eprint/63878 |
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