Pangerl, Jonas and Sukul, Pritam and Rueck, Thomas and Fuchs, Patricia and Weigl, Stefan and Miekisch, Wolfram and Bierl, Rudolf and Matysik, Frank-Michael (2024) An inexpensive UV-LED photoacoustic based real-time sensor-system detecting exhaled trace-acetone. PHOTOACOUSTICS, 38: 100604. ISSN 2213-5979
Full text not available from this repository. (Request a copy)Abstract
In this research we present a low-cost system for breath acetone analysis based on UV-LED photoacoustic spectroscopy. We considered the end-tidal phase of exhalation, which represents the systemic concentrations of volatile organic compounds (VOCs) - providing clinically relevant information about the human health. This is achieved via the development of a CO2-triggered breath sampling system, which collected alveolar breath over several minutes in sterile and inert containers. A real-time mass spectrometer is coupled to serve as a reference device for calibration measurements and subsequent breath analysis. The new sensor system provided a 3 sigma detection limit of 8.3 ppbV and an NNEA of 1.4E-9 Wcm(-1)Hz(-0.5). In terms of the performed breath analysis measurements, 12 out of 13 fell within the error margin of the photoacoustic measurement system, demonstrating the reliability of the measurements in the field.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | BREATH ACETONE; Photoacoustic spectroscopy; Real-time mass-spectrometry; Breath analysis; Acetone; UV-LED |
| Subjects: | 500 Science > 540 Chemistry & allied sciences |
| Divisions: | Chemistry and Pharmacy > Institut für Analytische Chemie, Chemo- und Biosensorik > Instrumentelle Analytik (Prof. Frank-Michael Matysik) |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 09 Dec 2025 09:36 |
| Last Modified: | 09 Dec 2025 09:36 |
| URI: | https://pred.uni-regensburg.de/id/eprint/63903 |
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