Schmitt, Jochen and Apfelbacher, Christian and Spuls, Phyllis I. and Thomas, Kim S. and Simpson, Eric L. and Furue, Masutaka and Chalmers, Joanne and Williams, Hywel C. (2015) The Harmonizing Outcome Measures for Eczema (HOME) Roadmap: A Methodological Framework to Develop Core Sets of Outcome Measurements in Dermatology. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 135 (1). pp. 24-30. ISSN 0022-202X, 1523-1747
Full text not available from this repository. (Request a copy)Abstract
Core outcome sets (COSs) are consensus-derived minimum sets of outcomes to be assessed in a specific situation. COSs are being increasingly developed to limit outcome-reporting bias, allow comparisons across trials, and strengthen clinical decision making. Despite the increasing interest in outcomes research, methods to develop COSs have not yet been standardized. The aim of this paper is to present the Harmonizing Outcomes Measures for Eczema (HOME) roadmap for the development and implementation of COSs, which was developed on the basis of our experience in the standardization of outcome measurements for atopic eczema. Following the establishment of a panel representing all relevant stakeholders and a research team experienced in outcomes research, the scope and setting of the core set should be defined. The next steps are the definition of a core set of outcome domains such as symptoms or quality of life, followed by the identification or development and validation of appropriate outcome measurement instruments to measure these core domains. Finally, the consented COS needs to be disseminated, implemented, and reviewed. We believe that the HOME roadmap is a useful methodological framework to develop COSs in dermatology, with the ultimate goal of better decision making and promoting patient-centered health care.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | CLINICAL-TRIALS; ATOPIC ECZEMA; CONSENSUS; QUALITY; OMERACT; IMPROVE; DOMAINS; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Institut für Epidemiologie und Präventivmedizin > Medical Sociology |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 05 Aug 2019 07:48 |
| Last Modified: | 05 Aug 2019 07:48 |
| URI: | https://pred.uni-regensburg.de/id/eprint/6391 |
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