Goetz, Andrea and Poschenrieder, Florian and Steer, Frederike Georgine and Zeman, Florian and Lange, Tobias J. and Thurn, Sylvia and Greiner, Barbara and Stroszczynski, Christian and Uller, Wibke and Hamer, Okka W. and Hammer, Simone (2024) Intravenous Opioid Medication with Piritramide Reduces the Risk of Pneumothorax During CT-Guided Percutaneous Core Biopsy of the Lung. CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY, 47 (5). pp. 621-631. ISSN 0174-1551, 1432-086X
Full text not available from this repository. (Request a copy)Abstract
Purpose CT-guided percutaneous core biopsy of the lung is usually performed under local anesthesia, but can also be conducted under additional systemic opioid medication. The purpose of this retrospective study was to assess the effect of intravenous piritramide application on the pneumothorax rate and to identify risk factors for post-biopsy pneumothorax.Materials and Methods One hundred and seventy-one core biopsies of the lung were included in this retrospective single center study. The incidence of pneumothorax and chest tube placement was evaluated. Patient-, procedure- and target-related variables were analyzed by univariate and multivariable logistic regression analysis.Results The overall incidence of pneumothorax was 39.2% (67/171). The pneumothorax rate was 31.5% (29/92) in patients who received intravenous piritramide and 48.1% (38/79) in patients who did not receive piritramide. In multivariable logistic regression analysis periinterventional piritramide application proved to be the only independent factor to reduce the risk of pneumothorax (odds ratio 0.46, 95%-confidence interval 0.24, 0.88; p = 0.018). Two or more pleura passages (odds ratio 3.38, 95%-confidence interval: 1.15, 9.87; p = 0.026) and prone position of the patient (odds ratio 2.27, 95%-confidence interval: 1.04, 4.94; p = 0.039) were independent risk factors for a higher pneumothorax rate.Conclusion Procedural opioid medication with piritramide proved to be a previously undisclosed factor decreasing the risk of pneumothorax associated with CT-guided percutaneous core biopsy of the lung.Level of Evidence 4 small study cohort.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | CHEST TUBE PLACEMENT; NEEDLE-BIOPSY; Computed tomography; Biopsy; Pneumothorax; Piritramide; Analgesics; Opioid; Risk factors |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Innere Medizin II Medicine > Lehrstuhl für Röntgendiagnostik Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Klinische Studien |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 29 Jul 2025 06:24 |
| Last Modified: | 29 Jul 2025 06:24 |
| URI: | https://pred.uni-regensburg.de/id/eprint/63970 |
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