Weber, Johanna and Scholz, Konstantin J. and Schenke, Isabelle M. and Pfab, Florian and Cieplik, Fabian and Hiller, Karl-Anton and Buchalla, Wolfgang and Sahm, Camilla and Kirschneck, Christian and Paddenberg-Schubert, Eva (2024) Randomized controlled clinical trial on the efficacy of a novel antimicrobial chewing gum in reducing plaque and gingivitis in adolescent orthodontic patients. CLINICAL ORAL INVESTIGATIONS, 28 (5): 272. ISSN 1432-6981, 1436-3771
Full text not available from this repository. (Request a copy)Abstract
Objectives Chewing gums containing antiseptics or other antimicrobial substances may be effective in reducing plaque and gingivitis. Therefore, the aim of this randomized placebo-controlled clinical trial was to investigate the efficacy of a novel antimicrobial chewing gum containing essential oils (cinnamon, lemon, peppermint) and extracts on reduction of dental plaque and gingivitis as well as on oral health-related quality of life (OHRQoL) in adolescent orthodontic patients.Materials 52 patients (11-22 years of age) were randomly assigned to use a test chewing gum (COVIDGUM, Clevergum) or a commercially available control chewing gum over a period of 10 days. Approximal plaque index (API), papillary bleeding index (PBI) and an OHRQoL questionnaire for children (COHIP-G19) were assessed at baseline (BL), after 10 days (10d) and 30 days (30d). In addition, oral health and oral hygiene related questions of the COHIP-G19 questionnaire were evaluated separately in subscales at each timepoint. Data were analyzed using non-parametrical statistical procedures (alpha = 0.05).Results API and PBI decreased significantly over time from BL to 10d and from BL to 30d in both groups, without significant differences between the groups. In both groups, the COHIP-G19 score, oral health subscale and oral hygiene subscale decreased significantly over time. Regarding the oral hygiene subscale, the test group showed significantly better scores at 30d (p = 0.011).Conclusion Both chewing gums performed similarly effective in terms of reducing plaque accumulation and gingival inflammation and improving OHRQoL.Clinical relevance Chewing gums without antimicrobial ingredients may be sufficient to decrease plaque accumulation and gingival inflammation.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ESSENTIAL-OIL; STREPTOCOCCUS-MUTANS; ORAL HYGIENE; HEALTH; CAPACITY; PARALLEL; XYLITOL; VERSION; Chewing gum; Essential oil; Plaque accumulation; Gingivitis; Orthodontic treatment |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Kieferorthopädie Medicine > Lehrstuhl für Zahnerhaltung und Parodontologie > Dr. rer. nat. Karl-Anton Hiller |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 13 Jan 2026 09:34 |
| Last Modified: | 13 Jan 2026 09:34 |
| URI: | https://pred.uni-regensburg.de/id/eprint/63974 |
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