Influence of Accumulation of Humidity under Wound Dressings and Effects on Transepidermal Water Loss (TEWL) and Skin Hydration

Rauscher, Marc and Rauscher, Andreas and Hu, Linda Y. and Schlitt, Hans J. and Krauss, Sabrina and Illg, Claudius and Wolfertstetter, Patricia Reis and Hofmann, Aybike and Knorr, Christian and Denzinger, Markus (2024) Influence of Accumulation of Humidity under Wound Dressings and Effects on Transepidermal Water Loss (TEWL) and Skin Hydration. APPLIED SCIENCES-BASEL, 14 (17): 7739. ISSN 2076-3417

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Abstract

The moisture content of the human skin, but also the loss of water through the skin, the transepidermal water loss (TEWL), plays a significant role in the skin's health. Various medical indications require the use of a wound dressing. However, how the skin environment changes under a wound dressing has not yet been sufficiently investigated. Skin moisture and TEWL values were measured in 20 healthy volunteers before and after the application of a total of 23 different wound dressings distributed over the back. Significant changes in the parameters from day 1 to day 2 were tested. Wound dressings change the underlying skin environment. Occlusive dressings significantly increase skin hydration and TEWL. The findings could contribute to quantitative analysis and monitoring of topical-wound therapy in the future.

Item Type: Article
Uncontrolled Keywords: water evaporation; skin microclimate; wound dressings; skin hydration; skin moisture
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Chirurgie
Medicine > Lehrstuhl für Kinder- und Jugendmedizin
Medicine > Institut für Funktionelle Genomik > Lehrstuhl für Statistische Bioinformatik (Prof. Spang)
Informatics and Data Science > Department Computational Life Science > Lehrstuhl für Statistische Bioinformatik (Prof. Spang)
Depositing User: Dr. Gernot Deinzer
Date Deposited: 30 Oct 2025 07:30
Last Modified: 30 Oct 2025 07:30
URI: https://pred.uni-regensburg.de/id/eprint/64004

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