Springorum, Hans-Robert and Baier, Clemens and Maderbacher, Gunther and Paulus, Alexander and Grifka, Joachim and Goetz, Juergen (2024) Periprosthetic Joint Infections of the Knee-Comparison of Different Treatment Algorithms. JOURNAL OF CLINICAL MEDICINE, 13 (13): 3718. ISSN , 2077-0383
Full text not available from this repository. (Request a copy)Abstract
Background: Periprosthetic joint infection (PJI) following total knee arthroplasty is a serious complication lacking evidence-based diagnostic and treatment protocols, particularly in ruling out persisting infection before reimplantation. Methods: This retrospective analysis assessed the mid-term outcomes of 66 patients undergoing septic two-stage knee revision surgeries from 2007 to 2013, diagnosed as per the Musculoskeletal Infection Society criteria. After implant removal and antibiotic treatment, reimplantation decisions were based on either joint aspiration, blood counts, and clinical examination (group A) or an open biopsy (group B). Both groups underwent meticulous debridement and spacer exchange during the interim period. Results: Late re-infection occurred in 12.1% of all patients. In group A, 13.8% experienced late re-infection, with 14.3% in subgroup A1 and 13.3% in subgroup A2. In group B, 10% had a late re-infection. No significant difference in re-infection or complication rates was found between the groups. Conclusions: The study did not demonstrate the superiority of group B's approach of open biopsy over group A's joint aspiration, clinical examination, and blood counts in preventing re-infection or reducing complications.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | TOTAL HIP-ARTHROPLASTY; C-REACTIVE PROTEIN; 2-STAGE EXCHANGE ARTHROPLASTY; RISK-FACTORS; ONE-STAGE; REVISION; REIMPLANTATION; DIAGNOSIS; CEMENT; GENTAMICIN; periprosthetic joint infection (PJI); total knee arthroplasty; joint aspiration; re-infection rate; revision surgery |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Orthopädie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 20 Jan 2026 10:39 |
| Last Modified: | 20 Jan 2026 10:39 |
| URI: | https://pred.uni-regensburg.de/id/eprint/64128 |
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