Hart, Christina and van Es, Nick and Voigtlaender, Minna (2025) Primary Prevention of Cancer-Associated Thrombosis: Current Perspectives. GEORG THIEME VERLAG KG, STUTTGART.
Full text not available from this repository. (Request a copy)Abstract
Over the past two decades, the incidence of cancer-associated thrombosis (CAT) has increased. It is nowadays a common and often serious complication among patients with cancer. Although medical thromboprophylaxis is recommended for most surgical and nonsurgical cancer patients, it has been infrequently used in ambulatory patients with cancer because of the burden of treatment and concerns about bleeding. However, various risk assessment scores are now available and randomized placebo-controlled trials have established the efficacy of low-molecular-weight heparin or the direct oral Xa inhibitors rivaroxaban and apixaban in ambulatory patients with cancer at high risk of venous thromboembolism (VTE). This review provides an overview of (1) primary thromboprophylaxis in the setting of hospitalized surgical and medical patients, (2) extended thromboprophylaxis after hospital discharge, (3) performance of risk assessment tools for CAT, and (4) primary thromboprophylaxis in ambulatory patients with cancer. The aim is to provide support to physicians in identifying ambulatory patients with cancer at high VTE risk who benefit most from medical thromboprophylaxis according to current recommendations from international guidelines.
| Item Type: | Other |
|---|---|
| Uncontrolled Keywords: | VENOUS THROMBOEMBOLISM PROPHYLAXIS; PATIENTS RECEIVING CHEMOTHERAPY; AMBULATORY PATIENTS; MEDICAL PATIENTS; EXTENDED THROMBOPROPHYLAXIS; ANTITHROMBOTIC PROPHYLAXIS; RISK-FACTORS; RIVAROXABAN; EFFICACY; SURGERY; cancer; thrombosis; prophylaxis; ambulatory patients; anticoagulants |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Innere Medizin III (Hämatologie und Internistische Onkologie) |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 17 Mar 2026 06:05 |
| Last Modified: | 17 Mar 2026 06:05 |
| URI: | https://pred.uni-regensburg.de/id/eprint/64229 |
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