Restifo, Nicholas P. and Gattinoni, Luca (2024) Synthetic soldiers: Turning T cells into immortal warriors. JOURNAL OF EXPERIMENTAL MEDICINE, 221 (5): e20240258. ISSN 0022-1007, 1540-9538
Full text not available from this repository. (Request a copy)Abstract
The creation of synthetic T cell states has captivated the field of cell-based therapies. Wang et al. describe how disruption of BCOR and ZC3H12A unleashes anti-tumor T cells with unprecedented lifespan and killer instinct. Are we witnessing the birth of immortal super-soldiers in medicine? The creation of synthetic T cell states has captivated the field of cell-based therapies. Wang et al. (https://doi.org/10.1084/jem.20232368) describe how disruption of BCOR and ZC3H12A unleashes anti-tumor T cells with unprecedented lifespan and killer instinct. Are we witnessing the birth of immortal super-soldiers in medicine?
| Item Type: | Article |
|---|---|
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Innere Medizin III (Hämatologie und Internistische Onkologie) |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 22 Oct 2025 07:59 |
| Last Modified: | 22 Oct 2025 07:59 |
| URI: | https://pred.uni-regensburg.de/id/eprint/64318 |
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