Lens injury as a complication of intravitreal medication injection

Clemens, Christoph R. and Alten, Florian and Eter, Nicole and Helbig, Horst and Maerker, David A. (2024) Lens injury as a complication of intravitreal medication injection. OPHTHALMOLOGIE, 121 (5). pp. 385-390. ISSN 2731-720X, 2731-7218

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Abstract

Background: Intravitreal medication injections are an efficient and low-risk delivery technique for treating various retinal diseases. Rare serious complications include increased intraocular pressure, vitreous hemorrhage, retinal tears and detachment, intraocular inflammation and endophthalmitis. In the case series presented here, we report iatrogenic lens injuries caused by inadequate performance of intravitreal injections. Methods: A multicenter data collection of patients treated with intravitreal injections with visible iatrogenic lens defects from 2016 to 2023 was retrospectively performed. Results: Lens trauma after intravitreal injections was identified in six cases (69.3 +/- 6.5 years). While five cases were observed after anti-VEGF therapy, we identified lens injury after dexamethasone implantation in one patient. Conclusion: Iatrogenic lens injury during intravitreal injection is preventable with the correct injection technique. Knowledge of individual axis length and lens status also helps to avoid this complication.

Item Type: Article
Uncontrolled Keywords: DEXAMETHASONE IMPLANT; RANIBIZUMAB; Quiescent lens injury; Intravitreal injection; Iatrogenic lens injury; Cataract; Posterior capsule rupture
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Augenheilkunde
Depositing User: Dr. Gernot Deinzer
Date Deposited: 07 Oct 2025 09:49
Last Modified: 07 Oct 2025 09:49
URI: https://pred.uni-regensburg.de/id/eprint/64347

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