Ichim, Cristian and Pavel, Vlad and Mester, Patricia and Schmid, Stephan and Todor, Samuel Bogdan and Stoia, Oana and Anderco, Paula and Kandulski, Arne and Mueller, Martina and Heumann, Philipp and Boicean, Adrian (2024) Assessing Key Factors Influencing Successful Resuscitation Outcomes in Out-of-Hospital Cardiac Arrest (OHCA). JOURNAL OF CLINICAL MEDICINE, 13 (23): 7399. ISSN , 2077-0383
Full text not available from this repository. (Request a copy)Abstract
Background: Out-of-hospital cardiac arrest (OHCA) is a critical health issue with survival influenced by multiple factors. This study analyzed resuscitation outcomes at the County Clinical Emergency Hospital of Sibiu, Romania, during pre-COVID-19 and pandemic periods. Methods: A retrospective analysis of 508 OHCA patients (2017-2020) assessed the return of spontaneous circulation (ROSC) as the primary endpoint. Statistical methods included decision tree analysis, logistic regression and ROC curve analysis to evaluate the predictive value of adrenaline dose and patient factors. Results: The mortality rate was 68.7%, with non-shockable rhythms predominant among fatalities. Rural patients, though younger, had lower ROSC rates than urban counterparts. Logistic regression showed that lower adrenaline doses (<= 4 mg, OR 11.835 [95% CI: 6.726-20.27]; 4-6 mg, OR 2.990 [95% CI: 1.773-5.042]) were associated with better ROSC outcomes. Conclusions: A multivariable model (AUC = 0.773) incorporating demographics and pandemic status outperformed adrenaline dose alone (AUC = 0.711).
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | CARDIOPULMONARY-RESUSCITATION; SPONTANEOUS CIRCULATION; DEATH; SURVIVAL; RISK; TIME; EPIDEMIOLOGY; ASSOCIATION; NATIONWIDE; COVID-19; resuscitation; return of spontaneous circulation; out-of-hospital cardiac arrest; adrenaline |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Innere Medizin I |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 26 Jan 2026 13:33 |
| Last Modified: | 26 Jan 2026 13:33 |
| URI: | https://pred.uni-regensburg.de/id/eprint/64489 |
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