He, Yu-Chuan and Yuan, Guo-Dong and Li, Nan and Ren, Mei-Fang and Qian-Zhang, and Deng, Kai-Ning and Wang, Le-Chuan and Xiao, Wei-Ling and Ma, Nan and Stamm, Christof and Felthaus, Oliver and Prantl, Lukas and Nie, Jia and Wang, Gang (2024) Recent advances in mesenchymal stem cell therapy for myocardial infarction. CLINICAL HEMORHEOLOGY AND MICROCIRCULATION, 87 (3). pp. 383-398. ISSN 1386-0291, 1875-8622
Full text not available from this repository. (Request a copy)Abstract
Myocardial infarction refers to the ischemic necrosis of myocardium, characterized by a sharp reduction or interruption of blood flow in the coronary arteries due to the coronary artery occlusion, resulting in severe and prolonged ischemia in the corresponding myocardium and ultimately leading to ischemic necrosis of the myocardium. Given its high risk, it is considered as one of the most serious health threats today. In current clinical practice, multiple approaches have been explored to diminish myocardial oxygen consumption and alleviate symptoms, but notable success remains elusive. Accumulated clinical evidence has showed that the implantation of mesenchymal stem cell for treating myocardial infarction is both effective and safe. Nevertheless, there persists controversy and variability regarding the standardizing MSC transplantation protocols, optimizing dosage, and determining the most effective routes of administration. Addressing these remaining issues will pave the way of integration of MSCs as a feasible mainstream cardiac treatment.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Myocardial infarction; mesenchymal stem cells; nanomaterials |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Plastische-, Hand- und Wiederherstellungschirurgie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 16 Oct 2025 07:07 |
| Last Modified: | 16 Oct 2025 07:07 |
| URI: | https://pred.uni-regensburg.de/id/eprint/64969 |
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