Peraio, Simone and Mantovani, Giorgio and Araceli, Tommaso and Mongardi, Lorenzo and Noris, Alice and Fino, Edoardo and Formica, Francesca and Piccinini, Luigi and Melani, Federico and Lenge, Matteo and Scalise, Roberta and Battini, Roberta and Di Rita, Andrea and D'Incerti, Ludovico and Appleton, Tayler and Cavallo, Michele Alessandro and Guerrini, Renzo and Giordano, Flavio (2024) Unilateral deep brain stimulation (DBS) of nucleus ventralis intermedius thalami (Vim) for the treatment of post-traumatic tremor in children: a multicentre experience. CHILDS NERVOUS SYSTEM, 40 (8). pp. 2457-2464. ISSN 0256-7040, 1433-0350
Full text not available from this repository. (Request a copy)Abstract
PurposeDeep brain stimulation (DBS) of nucleus ventralis intermedius thalami (Vim) is a validated technique for the treatment of essential tremor (ET) in adults. Conversely, its use for post traumatic tremor (PTT) and in paediatric patients is still debated. We evaluated the efficacy of Vim-DBS for lesional tremor in three paediatric patients with drug-resistant post-traumatic unilateral tremor.MethodsWe retrospectively collected data regarding three patients with unilateral tremor due to severe head injury, with no MRI evidence of basal ganglia lesions. The three patients underwent stereotactic frame-based robot-assisted DBS of Vim contralateral to the tremor side.ResultsMean follow-up was 48 months (range: 36-60 months). Tremor was reduced in all patients with a better control of voluntary movements and improvement of functional status (mean FIM scale improvement + 7 points). No surgical complications occurred.ConclusionUnilateral contralateral DBS of Vim could be efficacious in post-traumatic tremor, even in paediatric patients and should be offered in PTT drug-resistant patients.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ; Post traumatic tremor; Paediatric; Deep brain stimulation; Nucleus ventralis intermedius thalami |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Neurochirurgie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 11 Nov 2025 10:16 |
| Last Modified: | 11 Nov 2025 10:16 |
| URI: | https://pred.uni-regensburg.de/id/eprint/65019 |
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