Reike, Moritz J. and Reicherz, Alina and Tully, Karl H. and Bahlburg, Henning and Maas, Moritz and Bach, Peter and Kluemper, Niklas and Eckstein, Markus and Hartmann, Arndt and Breyer, Johannes and Erben, Philipp and Bolenz, Christian and Noldus, Joachim and Berg, Sebastian and Roghmann, Florian (2024) An Empirical Survey on the Adaption of Neoadjuvant Chemotherapy in Bladder Cancer. UROLOGIA INTERNATIONALIS, 108 (3). pp. 183-189. ISSN 0042-1138, 1423-0399
Full text not available from this repository. (Request a copy)Abstract
Introduction: The aim of the study was to determine the adaption of neoadjuvant chemotherapy (NAC) in patients with muscle-invasive bladder cancer (MIBC) in Germany, Austria, and Switzerland and especially underlying reasons for potential low adherence to guidelines. Methods: We conducted a non-validated survey among 336 urologic departments in Germany, Austria, and Switzerland. RedCap questionnaires were electronically distributed and included 23 items concerning the general NAC administration standards and guideline compliance in patient counseling regarding the actual treatment. Results: The return rate of the questionnaire was 19.1% (63/336). Although 45 departments (71.4%) claim to perform NAC as the standard of care, only 49% of eligible patients actually receive NAC. An advanced disease stage (>= cT3) and a high tumor volume were mentioned to support the application of NAC, whereas 35% of responders worry about deterioration of patients' preoperative status due to NAC. Furthermore, 26.7% of respondents are concerned about the low extent of survival benefit. Conclusion: Application of NAC in eligible MIBC patients in Germany, Austria, and Switzerland remains low. Although the majority of urologic departments discuss NAC and acknowledge the need for intensified treatment in advanced disease stages, not all eligible patients will actually receive NAC before radical cystectomy.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | RADICAL CYSTECTOMY; UROTHELIAL CARCINOMA; Bladder cancer; Neoadjuvant chemotherapy; Radical cystectomy; Empirical study; Germany |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Urologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 17 Dec 2025 06:38 |
| Last Modified: | 17 Dec 2025 06:38 |
| URI: | https://pred.uni-regensburg.de/id/eprint/65085 |
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