Association of Diabetic Ketoacidosis in Childhood New-Onset Type 1 Diabetes With Day of Presentation in Germany

Kamrath, Clemens and Sindichakis, Marina and Auzanneau, Marie and Schmid, Silke and Segerer, Hugo and Lahn, Valentina and Golembowsky, Sven and Roessner-Cold, Dorothee and Rauh, Kristina and Manuwald, Ulf and Holl, Reinhard W. (2024) Association of Diabetic Ketoacidosis in Childhood New-Onset Type 1 Diabetes With Day of Presentation in Germany. DIABETES CARE, 47 (4). pp. 649-652. ISSN 0149-5992, 1935-5548

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Abstract

OBJECTIVE Whether the day of the week on which the child presents affects timely diagnosis and risk of diabetic ketoacidosis (DKA) in children with new-onset type 1 diabetes (T1D) is not known. RESEARCH DESIGN AND METHODS We used data of 30,717 children with new-onset T1D during the last 10 years from the German Prospective Diabetes Registry. We determined the odds ratios of T1D diagnosis and DKA on a weekday, public holiday, and school vacation. RESULTS Compared with workdays, the odds ratios of being diagnosed with T1D were lower on weekends (0.39 [95% CI, 0.38-0.41]), public holidays (0.57 [0.53-0.63]), and school vacations (0.83 [0.80-0.85]). The odds of DKA diagnosis were also reduced on weekends (0.55 [0.52-0.59]), public holidays (0.73 [0.63-0.84]), and school vacations (0.85 [0.80-0.90]). Results did not change during the coronavirus 2019 pandemic. CONCLUSIONS New-onset T1D and DKA in children are more often diagnosed during weekdays than weekends and holidays.

Item Type: Article
Uncontrolled Keywords: DIAGNOSIS; CHILDREN;
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Kinder- und Jugendmedizin
Depositing User: Dr. Gernot Deinzer
Date Deposited: 17 Dec 2025 08:01
Last Modified: 17 Dec 2025 08:01
URI: https://pred.uni-regensburg.de/id/eprint/65109

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