Jaekel, Anke K. and Rieger, Julia and Butscher, Anna-Lena and Moehr, Sandra and Schindler, Oliver and Queissert, Fabian and Hofmann, Aybike and Schmidt, Paul and Kirschner-Hermanns, Ruth and Knuepfer, Stephanie C. (2024) Diagnoses and Treatment Recommendations-Interrater Reliability of Uroflowmetry in People with Multiple Sclerosis. BIOMEDICINES, 12 (7): 1598. ISSN 2227-9059
Full text not available from this repository. (Request a copy)Abstract
Background: Uroflowmetry (UF) is an established procedure in urology and is recommended before further investigations of neurogenic lower urinary tract dysfunction (NLUTD). Some authors even consider using UF instead of urodynamics (UD). Studies on the interrater reliability of UF regarding treatment recommendations are rare, and there are no relevant data on people with multiple sclerosis (PwMS). The aim of this study was to investigate the interrater reliability (IRR) of UF concerning diagnosis and therapy in PwMS prospectively. Methods: UF of 92 PwMS were assessed by 4 raters. The diagnostic criteria were normal findings (NFs), detrusor overactivity (DO), detrusor underactivity (DU), detrusor-sphincter dyssynergia (DSD) and bladder outlet obstruction (BOO). The possible treatment criteria were as follows: no treatment (NO), catheter placement (CAT), alpha-blockers, detrusor-attenuating medication, botulinum toxin (BTX), neuromodulation (NM), and physiotherapy/biofeedback (P/BF). IRR was assessed by kappa (kappa). Results: kappa of diagnoses were NFs = 0.22; DO = 0.17; DU = 0.07; DSD = 0.14; and BOO = 0.18. For therapies, the highest kappa was BTX = 0.71, NO = 0.38 and CAT = 0.44. Conclusions: There is a high influence of the individual rater. UD should be subject to the same analysis and a comparison should be made between UD and UF. This may have implications for the value of UF in the neuro-urological management of PwMS, although at present UD remains the gold standard for the diagnostics of NLUTD in PwMS.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | GOOD URODYNAMIC PRACTICES; LOWER URINARY-TRACT; DETRUSOR UNDERACTIVITY; BLADDER; CYSTOMETRY; CURVES; multiple sclerosis; bladder disorder; neurogenic; bladder |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Kinder- und Jugendmedizin |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 22 Jan 2026 05:55 |
| Last Modified: | 22 Jan 2026 05:55 |
| URI: | https://pred.uni-regensburg.de/id/eprint/65110 |
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