Hoffmann, Ada and Hoffmann, Joergen and Ruegamer, Tamara and Jung, Norma and Wong, Ronald Man Yeung and Alt, Volker and Eysel, Peer and Jantsch, Jonathan (2024) New diagnostic techniques for diagnosing facture-related infections. INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED, 55: 111898. ISSN 0020-1383, 1879-0267
Full text not available from this repository. (Request a copy)Abstract
The diagnosis of fracture-related infections (FRI) is challenging and requires interdisciplinary efforts. Many diagnostic approaches are based on the algorithms established for prosthetic joint infections (PJI). Data specific to FRI are limited. Microbiological diagnostics include tissue culture, sonication, and molecular methods. Novel metagenomic analyses are increasingly being used in clinical diagnostic practice. In addition to bacterial detection, the study of host tissue factors has the potential to transform the diagnostics of FRI by facilitating the assesment of clinical significance in clinical samples. The integration of host tissue analysis into microbiology reports has great potential to improve the diagnosis of FRI. This mini-review describes the potential improvement of diagnostic techniques by integrating new approaches into the diagnostic algorithm of fracture-related infections.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | PROSTHETIC-JOINT INFECTION; FRACTURE-RELATED INFECTION; BROAD-RANGE PCR; SONICATION; ARTHROPLASTY; FIXATION; KNEE; HIP; OSTEOMYELITIS; ACCURACY; Fracture-related infection; Culture; Sonication; Mircobiological diagnostics; Host factors |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Unfallchirurgie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 16 Jan 2026 12:53 |
| Last Modified: | 16 Jan 2026 12:53 |
| URI: | https://pred.uni-regensburg.de/id/eprint/65299 |
Actions (login required)
 |
View Item |
