Teusch, V. I. and Piehler, A. P. and Uller, W. and Mueller-Wille, R. and Prantl, L. and Stroszczynski, C. and Wohlgemuth, W. A. and Jung, E. M. (2017) Value of different ultrasound elastography techniques in patients with venous malformations prior to and after sclerotherapy. CLINICAL HEMORHEOLOGY AND MICROCIRCULATION, 66 (4). pp. 347-355. ISSN 1386-0291, 1875-8622
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AIM: Comparison of different ultrasound elastography techniques for detection of changes after sclerotherapy within venous malformations. MATERIALANDMETHODS: In patients with venous malformations sonographywas executed at exactly the same position prior to and after ethanol-gel sclerotherapy. Both examinations included B-Mode, vascular sonography with Color-Coded Duplex Sonography, and additional sonography with different elastography techniques (strain, qualitative and quantitative Acoustic Radiation Force Impulse (ARFI) elastography) with a linear transducer (6-9 MHz). Qualitative elastograms were read in consensus and scored. Differences of elasticity scores were statistically analyzed, p-values < 0.05 were regarded significant. RESULTS: Elasticity scores of strain and qualitative ARFI elastography in 25 patients (21 females, averagely 24.4 years old) were comparable before treatment (p = 0.69). After therapy qualitative ARFI scores changed significantly compared to pre-treatment scores (p = 0.0017), whereas strain elastography scores revealed no significant changes (p = 0.13). Quantitative ARFI values obtained after sclerotherapy within the venous malformations were significantly higher compared to pretreatment values (p = 0.049), and significantly higher to values obtained in surrounding tissue (p = 0.030). Comparison of preand post-treatment ARFI values of the surrounding tissue was not significant (p = 0.67). CONCLUSION: Elasticity scores of qualitative ARFI elastography reliably detect ethanol-gel induced changes in venous malformations. Quantitative ARFI may be a tool for therapy planning, and for monitoring sclerotherapy outcome as well as the effect of sclerosing agents on malformation and surrounding tissue in patients with venous malformations.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | FLOW VASCULAR MALFORMATIONS; IMPULSE ARFI ELASTOGRAPHY; DIAGNOSIS; CLASSIFICATION; MANAGEMENT; Venous malformation; elastography; elasticity score; Acoustic Radiation Force Impulse (ARFI) imaging; therapy control |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Chirurgie Medicine > Lehrstuhl für Röntgendiagnostik |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 14 Dec 2018 13:01 |
| Last Modified: | 26 Feb 2019 07:08 |
| URI: | https://pred.uni-regensburg.de/id/eprint/654 |
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