Extracorporeal Life Support Organization Registry International Report 2022: 100,000 Survivors

Tonna, Joseph E. and Boonstra, Philip S. and MacLaren, Graeme and Paden, Matthew and Brodie, Daniel and Anders, Marc and Hoskote, Aparna and Ramanathan, Kollengode and Hyslop, Rob and Fanning, Jeffrey J. and Rycus, Peter and Stead, Christine and Barrett, Nicholas A. and Mueller, Thomas and Gomez, Rene D. and Kapoor, Poonam Malhotra and Fraser, John F. and Bartlett, Robert H. and Alexander, Peta M. A. and Barbaro, Ryan P. (2024) Extracorporeal Life Support Organization Registry International Report 2022: 100,000 Survivors. ASAIO JOURNAL, 70 (2). pp. 131-143. ISSN 1058-2916, 1538-943X

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Abstract

The Extracorporeal Life Support Organization (ELSO) maintains the world's largest extracorporeal membrane oxygenation (ECMO) registry by volume, center participation, and international scope. This 2022 ELSO Registry Report describes the program characteristics of ECMO centers, processes of ECMO care, and reported outcomes. Neonates (0-28 days), children (29 days-17 years), and adults (>= 18 years) supported with ECMO from 2009 through 2022 and reported to the ELSO Registry were included. This report describes adjunctive therapies, support modes, treatments, complications, and survival outcomes. Data are presented descriptively as counts and percent or median and interquartile range (IQR) by year, group, or level. Missing values were excluded before calculating descriptive statistics. Complications are reported per 1,000 ECMO hours. From 2009 to 2022, 154,568 ECMO runs were entered into the ELSO Registry. Seven hundred and eighty centers submitted data during this time (557 in 2022). Since 2009, the median annual number of adult ECMO runs per center per year increased from 4 to 15, whereas for pediatric and neonatal runs, the rate decreased from 12 to 7. Over 50% of patients were transferred to the reporting ECMO center; 20% of these patients were transported with ECMO. The use of prone positioning before respiratory ECMO increased from 15% (2019) to 44% (2021) for adults during the coronavirus disease-2019 (COVID-19) pandemic. Survival to hospital discharge was greatest at 68.5% for neonatal respiratory support and lowest at 29.5% for ECPR delivered to adults. By 2022, the Registry had enrolled its 200,000th ECMO patient and 100,000th patient discharged alive. Since its inception, the ELSO Registry has helped centers measure and compare outcomes across its member centers and strategies of care. Continued growth and development of the Registry will aim to bolster its utility to patients and centers.

Item Type: Article
Uncontrolled Keywords: HOSPITAL CARDIAC-ARREST; MEMBRANE-OXYGENATION; CARDIOPULMONARY-RESUSCITATION; EARLY MOBILIZATION; CARDIOGENIC-SHOCK; COVID-19; MOBILITY; ADULTS; ECMO; extracorporeal life support; extracorporeal membrane oxygenation; survival; cardiogenic shock; respiratory failure; extracorporeal cardiopulmonary resuscitation
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Innere Medizin II
Depositing User: Dr. Gernot Deinzer
Date Deposited: 06 Aug 2025 06:10
Last Modified: 06 Aug 2025 06:10
URI: https://pred.uni-regensburg.de/id/eprint/65687

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