Schweiger, Victor and Cammann, Victoria L. and Crisci, Giulia and Gilhofer, Thomas and Schlenker, Rabea and Niederseer, David and Chen, Shaojie and Ebrahimi, Ramin and Wenzl, Florian and Wurdinger, Michael and Citro, Rodolfo and Vecchione, Carmine and Gili, Sebastiano and Neuhaus, Michael and Franke, Jennifer and Meder, Benjamin and Jaguszewski, Milosz and Noutsias, Michel and Knorr, Maike and Jansen, Thomas and D'Ascenzo, Fabrizio and Dichtl, Wolfgang and von Lewinski, Dirk and Burgdorf, Christof and Kherad, Behrouz and Tschoepe, Carsten and Sarcon, Annahita and Shinbane, Jerold and Rajan, Lawrence and Michels, Guido and Pfister, Roman and Cuneo, Alessandro and Jacobshagen, Claudius and Karakas, Mahir and Koenig, Wolfgang and Pott, Alexander and Meyer, Philippe and Roffi, Marco and Banning, Adrian and Wolfrum, Mathias and Cuculi, Florim and Kobza, Richard and Fischer, Thomas A. and Vasankari, Tuija and Airaksinen, K. E. Juhani and Napp, L. Christian and Dworakowski, Rafal and MacCarthy, Philip and Kaiser, Christoph and Osswald, Stefan and Galiuto, Leonarda and Chan, Christina and Bridgman, Paul and Beug, Daniel and Delmas, Clement and Lairez, Olivier and Gilyarova, Ekaterina and Shilova, Alexandra and Gilyarov, Mikhail and El-Battrawy, Ibrahim and Akin, Ibrahim and Polednikova, Karolina and Tousek, Petr and Winchester, David E. and Massoomi, Michael and Galuszka, Jan and Ukena, Christian and Poglajen, Gregor and Carrilho-Ferreira, Pedro and Hauck, Christian and Paolini, Carla and Bilato, Claudio and Kobayashi, Yoshio and Kato, Ken and Ishibashi, Iwao and Himi, Toshiharu and Din, Jehangir and Al-Shammari, Ali and Prasad, Abhiram and Rihal, Charanjit S. and Liu, Kan and Schulze, P. Christian and Bianco, Matteo and Jorg, Lucas and Rickli, Hans and Pestana, Goncalo and Nguyen, Thanh H. and Boehm, Michael and Maier, Lars S. and Pinto, Fausto J. and Widimsky, Petr and Felix, Stephan B. and Braun-Dullaeus, Ruediger C. and Rottbauer, Wolfgang and Hasenfuss, Gerd and Pieske, Burkert M. and Schunkert, Heribert and Budnik, Monika and Opolski, Grzegorz and Thiele, Holger and Bauersachs, Johann and Horowitz, John D. and Di Mario, Carlo and Kong, William and Dalakoti, Mayank and Imori, Yoichi and Muenzel, Thomas and Liberale, Luca and Montecucco, Fabrizio and Bax, Jeroen J. and Crea, Filippo and Ruschitzka, Frank and Luscher, Thomas F. and Ghadri, Jelena R. and Bossone, Eduardo and Templin, Christian and Di Vece, Davide (2024) Temporal Trends in Takotsubo Syndrome Results From the International Takotsubo Registry. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 84 (13). pp. 1178-1189. ISSN 0735-1097, 1558-3597
Full text not available from this repository. (Request a copy)Abstract
BACKGROUND The perception of takotsubo syndrome (TTS) has evolved significantly over the years, primarily driven by increased recognition of acute complications and mortality. OBJECTIVES This study aimed to explore temporal trends in demographic patterns, risk factors, clinical presentations, and outcomes in patients with TTS. METHODS Patients diagnosed with TTS between 2004 and 2021 were enrolled from the InterTAK (International Takotsubo) registry. To assess temporal trends, patients were divided into 6 groups, each corresponding to a 3-year interval within the study period. RESULTS Overall, 3,957 patients were included in the study. There was a significant demographic transition, with the proportion of male patients rising from 10% to 15% (P = 0.003). Although apical TTS remained the most common form, the diagnosis of midventricular TTS increased from 18% to 28% (P = 0.018). The prevalence of physical triggers increased from 39% to 58% over the years (P < 0.001). There was a significant increase in 60-day mortality over the years (P < 0.001). However, a landmark analysis excluding patients who died within the first 60 days showed no differences in 1-year mortality (P = 0.150). CONCLUSIONS This study of temporal trends in TTS highlights a transition in patients demographic with a growing prevalence among men, increasing recognition of midventricular TTS type, and increased short-term mortality and rates of cardiogenic shock in recent years. This transition aligns with the rising prevalence of physical triggers, as expression of increased recognition of TTS in association with acute comorbidities. (c) 2024 by the American College of Cardiology Foundation.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | MYOCARDIAL-INFARCTION; CLINICAL PROFILE; TAKO-TSUBO; OUTCOMES; broken heart syndrome; stress cardiomyopathy; takotsubo syndrome; trends |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Innere Medizin II |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 23 Jul 2025 08:33 |
| Last Modified: | 23 Jul 2025 08:33 |
| URI: | https://pred.uni-regensburg.de/id/eprint/65762 |
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