Position paper for the standardized use of transjugular intrahepatic portosystemic shunt (TIPS) in adults

Trebicka, Jonel and Steib, Christian and Zipprich, Alexander and Ripoll, Cristina and Kluwe, Johannes and Schultheiss, Michael and Schnitzbauer, Andreas A. and Meyer, Bernhard and Jansen, Christian and Heinzow, Hauke and Papprottka, Philipp and Meyer, Carsten and Seidensticker, Max and Ittrich, Harald and Uschner, Frank Erhard and Gu, Wenyi and Aehling, Niklas and Neumann, Ulf and Caca, Karel and Kohler, Michael and Seifert, Leon Louis and Betinger, Dominik and Bruns, Tony and Dollinger, Matthias and Praktiknjo, Michael and Berg, Thomas and Wildgruber, Moritz and Pitton, Michael B. and Goessmann, Holger and Gerbes, Alexander and Rossle, Martin and Wedemeyer, Heiner and Denzer, Ulrike and Lynen, Petra (2025) Position paper for the standardized use of transjugular intrahepatic portosystemic shunt (TIPS) in adults. ZEITSCHRIFT FUR GASTROENTEROLOGIE, 63 (11). pp. 1149-1181. ISSN 0044-2771, 1439-7803

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Abstract

Portal hypertension is associated with significant morbidity and mortality. Liver cirrhosis accounts for up to 90 % of portal hypertension cases, while approximately 10 % are due to non-cirrhotic factors, including vascular liver diseases. This condition can lead to various complications, such as the development of gastroesophageal varices, which greatly increase the risk of variceal bleeding. Other common complications of portal hypertension include ascites and hepatorenal syndrome (HRS). The transjugular intrahepatic portosystemic shunt (TIPS) procedure is regarded as the most effective treatment for managing portal hypertension. Research shows that TIPS insertion can improve survival rates for patients with recurrent ascites, as well as for select individuals with refractory ascites and variceal bleeding. However, peri-interventional and post-interventional complications may pose challenges to the use of TIPS. Recent advancements in devices, techniques, and prophylactic medications aim to minimize the risk of complications following this procedure. This interdisciplinary position paper summarizes recommendations and guidance regarding patient selection, indications and contraindications, techniques, and follow-up care for patients undergoing TIPS in Germany.

Item Type: Article
Uncontrolled Keywords: BUDD-CHIARI-SYNDROME; PORTAL-VEIN THROMBOSIS; SEVERE VENOOCCLUSIVE DISEASE; REFRACTORY HEPATIC-ENCEPHALOPATHY; CRITICAL FLICKER FREQUENCY; STEM-CELL TRANSPLANTATION; SEGMENTAL LIVER ISCHEMIA; BLEEDING ECTOPIC VARICES; LONG-TERM; COVERED STENTS; TIPS; Liver; Liver Cirrhosis; Portal Hypertension; Liver; Liver Cirrhosis; Portal Hypertension
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Chirurgie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 30 Mar 2026 09:29
Last Modified: 30 Mar 2026 09:29
URI: https://pred.uni-regensburg.de/id/eprint/67920

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