Consistencies in Follow-up After Radical Cystectomy for Bladder Cancer: A Framework Based on Expert Practices Collaboratively Developed by the European Association of Urology Bladder Cancer Guideline Panels

Mertens, Laura S. and Bruins, Harman Maxim and Contieri, Roberto and Babjuk, Marek and Rai, Bhavan P. and Puig, Albert Carrion and Escrig, Jose Luis Dominguez and Gontero, Paolo and van der Heijden, Antoine G. and Liedberg, Fredrik and Martini, Alberto and Masson-Lecomte, Alexandra and Meijer, Richard P. and Mostafid, Hugh and Neuzillet, Yann and Pradere, Benjamin and Redlef, John and van Rhijn, Bas W. G. and Rouanne, Matthieu and Roupret, Morgan and Saebjornsen, Saebjorn and Seisen, Thomas and Shariat, Shahrokh F. and Soria, Francesco and Soukup, Viktor and Thalmann, George and Xylinas, Evanguelos and Mariappan, Paramananthan and Witjes, J. Alfred (2025) Consistencies in Follow-up After Radical Cystectomy for Bladder Cancer: A Framework Based on Expert Practices Collaboratively Developed by the European Association of Urology Bladder Cancer Guideline Panels. EUROPEAN UROLOGY ONCOLOGY, 8 (1). pp. 105-110. ISSN , 2588-9311

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Abstract

Background and objective: There is no standardized regimen for follow-up after radical cystectomy (RC) for bladder cancer (BC). To address this gap, we conducted a multicenter study involving urologist members from the European Association of Urology (EAU) bladder cancer guideline panels. Our objective was to identify consistent post-RC follow-up strategies and develop a practice-based framework based on expert opinion. Methods: We surveyed 27 urologist members of the EAU guideline panels for non-muscle-invasive bladder cancer and muscle-invasive and metastatic bladder cancer using a pre-tested questionnaire with dichotomous responses. The survey inquired about follow-up strategies after RC and the use of risk-adapted strategies. Consistency was defined as >75% affirmative responses for follow-up practices commencing 3 mo after RC. Descriptive statistics were used for analysis. Key findings and limitations: We received responses from 96% of the panel members, who provided data from 21 European hospitals. Risk-adapted follow-up is used in 53% of hospitals, with uniform criteria for high-risk (at least >= pT3 or pN+) and low-risk ([y]pT0/a/1N0) cases. In the absence of agreement for risk-based follow up, a non-risk-adapted framework for follow-up was developed. Higher conformity was observed within the initial 3 yr, followed by a decline in subsequent follow-up. Follow-up was most frequent during the first year, including patient assessments, physical examinations, and laboratory tests. Computed tomography of the chest and abdomen/pelvis was the most common imaging modality, initially at least biannually, and then annually from years 2 to 5. There was a lack of consistency for continuing follow-up beyond 10 yr after RC. Conclusions and clinical implications: This practice-based post-RC follow-up framework developed by EAU bladder cancer experts may serve as a valuable guide for urologists in the absence of prospective randomized studies.

Item Type: Article
Uncontrolled Keywords: OUTCOMES; Bladder cancer; Urothelial carcinoma; Cystectomy; Follow-up; Imaging
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Urologie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 26 Mar 2026 12:36
Last Modified: 26 Mar 2026 12:36
URI: https://pred.uni-regensburg.de/id/eprint/67992

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