Differential diagnosis of granulomatous diseases

Ehrenstein, B. and Brochhausen, C. (2017) Differential diagnosis of granulomatous diseases. ZEITSCHRIFT FUR RHEUMATOLOGIE, 76 (5). pp. 415-423. ISSN 0340-1855, 1435-1250

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Abstract

Despite advances in the understanding of the pathophysiology, granulomatous diseases remain a diagnostic challenge for the clinician as well as for the pathologist. However, establishing the correct diagnosis of these diseases is a crucial prerequisite of targeted therapy. It is particularly essential to distinguish between an infectious and a non-infectious cause, since anti-infectious and anti-inflammatory or immunosuppressive approaches are opposing. Failure to establish the correct diagnosis can lead to adverse consequences for the patient. An interdisciplinary approach and a critical assessment of clinical, laboratory-chemical, microbiological, imaging, and anatomical-pathological findings are crucial for the evaluation of granulomatous disorders. This overview summarizes important landmarks and their value in the interplay of arriving at the correct diagnosis.

Item Type: Article
Uncontrolled Keywords: HISTOLOGIC FEATURES; UNITED-STATES; SARCOIDOSIS; DISORDERS; PULMONARY; PATTERNS; LUNG; Granuloma; Biopsy; Mycobacterial infections; Fungal infections; Opportunistic infections
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Pathologie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 14 Dec 2018 13:10
Last Modified: 18 Feb 2019 13:08
URI: https://pred.uni-regensburg.de/id/eprint/749

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