Hufnagel, Anna and Frick, Ulrich and Ridinger, Monika and Wodarz, Norbert (2017) Recovery from alcohol dependence: Do smoking indicators predict abstinence? AMERICAN JOURNAL ON ADDICTIONS, 26 (4). pp. 366-373. ISSN 1055-0496, 1521-0391
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Background and ObjectivesThere is inconsistent evidence about the potential influence of smoking on recovery from alcohol dependence. Our study aimed at assessing the impact of smoking-behavior on relapse during a 12 months follow-up period following a detoxification in patients with Alcohol Use Disorder (AUD). MethodsThree hundred Patients with AUD (74.9% smoking) were recruited from two inpatient detoxification units in psychiatric hospitals in Germany and their alcohol consumption was prospectively followed for 1 year. Data on different indicators of smoking behavior was gathered. Cox regression model was used to evaluate potential risk factors on time to relapse of alcohol consumption. Two hundred seventy-nine participants (n=279) were included in the final analysis. ResultsSmoking increased the risk for alcohol relapse (hazard ratio=3.962, 95% CI 1.582-9.921). However, this increased risk is slightly reduced with higher numbers of daily consumed cigarettes (hazard ratio per cigarette=.986, 95% CI .976-.995). ConclusionSmoking reduced the probability of maintaining alcohol abstinence significantly, whereas higher number of cigarettes smoked daily diminished the increased risk of alcohol relapse in alcohol-dependent patients. Scientific SignificanceCoordinated psychiatric and substance abuse interventions for different subgroups of patients with AUD in the post-acute treatment phase are necessary. Individualized treatment planning is especially important in smoking patients with AUD who are vulnerable for a relapse to alcohol drinking and for somatic complications. Our findings might support individualized treatment plans. (Am J Addict 2017;26:366-373)
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | SELF-REPORTED SMOKING; CIGARETTE-SMOKING; NICOTINE DEPENDENCE; USE DISORDERS; FOLLOW-UP; RELAPSE; RISK; DRINKING; ABUSE; RATES; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Psychiatrie und Psychotherapie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 14 Dec 2018 13:10 |
| Last Modified: | 12 Feb 2019 13:20 |
| URI: | https://pred.uni-regensburg.de/id/eprint/837 |
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