Synthesis and Regioselectivity in the Alkylation of 1,3,4-Oxadiazolethiones with Dihaloalkanes and Epichlorohydrin

El Ashry, El Sayed H. and Boraei, Ahmed T. A. and Duerkop, Axel (2017) Synthesis and Regioselectivity in the Alkylation of 1,3,4-Oxadiazolethiones with Dihaloalkanes and Epichlorohydrin. JOURNAL OF HETEROCYCLIC CHEMISTRY, 54 (1). pp. 95-101. ISSN 0022-152X, 1943-5193

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Abstract

[GRAPHICS] The regioselectivity in the alkylation of 1,3,4-oxadiazolethiones with dihaloalkanes was found that it depends mainly on the length of the alkyl chain connecting the two halides; moreover, the formation of thiirane ring instead of epoxide ring during the alkylation with epichlorohydrin was surprising.

Item Type: Article
Uncontrolled Keywords: BIOLOGICAL EVALUATION; ANTICANCER ACTIVITY; DERIVATIVES; ANTITUMOR; AGENTS; ACID;
Subjects: 500 Science > 540 Chemistry & allied sciences
Divisions: Chemistry and Pharmacy > Institut für Analytische Chemie, Chemo- und Biosensorik
Depositing User: Dr. Gernot Deinzer
Date Deposited: 14 Dec 2018 12:58
Last Modified: 12 Feb 2019 09:28
URI: https://pred.uni-regensburg.de/id/eprint/85

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