Acquired Neuromuscular Transmission Disorders: Myasthenias and Lambert-Eaton Syndrome

Kirzinger, L. and Schalke, B. (2014) Acquired Neuromuscular Transmission Disorders: Myasthenias and Lambert-Eaton Syndrome. KLINISCHE NEUROPHYSIOLOGIE, 45 (4). pp. 193-200. ISSN 1434-0275, 1439-4081

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Abstract

The group of acquired myasthenic syndromes can be divided into the postsynaptic myasthenias (MG) and the presynaptic Lambert-Eaton syndrome (LEMS). By improvement of diagnostic procedures (receptor-auto-antibody testing, electrophysiology, imaging, pharmacological testing) it is possible to refer the specific diseases to pathophysiologically defined subgroups. This enables a better and more specific therapy, e.g., indication for thymectomy or no thymectomy, different or more specific use of cholinesterase inhibitors for symptomatic treatment. Having more selective diagnostic as a consequence of the better pathophysiological understanding of the underlying processes at the neuromuscular synapsis, it is possible to use therapies more selectively, to avoid medical malpractice and to provide a better satisfaction for the patient.

Item Type: Article
Uncontrolled Keywords: QUALITY STANDARDS SUBCOMMITTEE; RANDOMIZED-TRIAL; DOUBLE-BLIND; OCULAR MYASTHENIA; AMERICAN-ACADEMY; ANTI-ACHR; GRAVIS; DRUG; MUSK; 3,4-DIAMINOPYRIDINE; Myasthenia gravis; neuromuscular diseases; Myasthenias; Lambert-Eaton Syndrome
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Neurologie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 07 Aug 2019 08:43
Last Modified: 07 Aug 2019 08:43
URI: https://pred.uni-regensburg.de/id/eprint/9110

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