Lejeune, Alice and Cremer, Malte and von Bernuth, Horst and Edelmann, Anke and Modrow, Susanne and Buehrer, Christoph (2014) Persistent pure red cell aplasia in dicygotic twins with persistent congenital parvovirus B19 infection-remission following high dose intravenous immunoglobulin. EUROPEAN JOURNAL OF PEDIATRICS, 173 (12). pp. 1723-1726. ISSN 0340-6199, 1432-1076
Full text not available from this repository. (Request a copy)Abstract
We report the course of dicygotic twins born preterm after 29 (4)/(7) weeks of gestation due to congenital Parvovirus B19 infection causing fetal hydrops with severe anemia in one infant in whom intrauterine transfusion was impossible to perform and high levels of viremia in both infants. After being discharged, they were readmitted at 3 months of age with critical aplastic crisis. Therapy with intravenous immunoglobulin infusion resulted in decreasing viremia followed by stable hemoglobin levels in both infants. Conclusion: Intravenous immunoglobulin treatment of congenital pure red cell aplasia due to Parvovirus B19 infection in preterm infants seems to be effective to introduce viral remission and to normalize erythropoiesis.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | PREGNANCY; Parvovirus B19; Congenital pure red cell aplasia; IVIG; Neonate; Anemia |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 07 Aug 2019 09:25 |
| Last Modified: | 07 Aug 2019 09:25 |
| URI: | https://pred.uni-regensburg.de/id/eprint/9145 |
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