Predictors of non-transplantation of adult donor organs - an observational study using routine data from Eurotransplant

Drewitz, Karl Philipp and Loss, Martin and Loss, Julika and Apfelbacher, Christian Joachim (2014) Predictors of non-transplantation of adult donor organs - an observational study using routine data from Eurotransplant. BMC HEALTH SERVICES RESEARCH, 14: 584. ISSN 1472-6963,

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Abstract

Background: The majority of pancreases, offered in allocation, are not transplanted. This pancreas under-utilisation is a phenomenon observed in all transplant systems in North-America and Europe. It was the aim of this study to analyse factors predictive of pancreas non-transplantation in Germany. Methods: Routine Eurotransplant data of 3,666 deceased German donors (from 2002-2011) were used for multivariate modelling. Socio-demographic and medical factors were considered as independent variables in logistic regression models with non-transplantation as dependent variable. Results: Male gender, advanced age, overweight/obesity, long ICU stay, a history of smoking, non-traumatic brain death, elevated levels of sodium, serum glucose, lipase/amylase and the liver not being considered for procurement were significant independent predictors of non-transplantation. Conclusion: In line with previous research, advanced age, high BMI, long ICU stay and the liver not being considered for procurement were the strongest predictors of pancreas non-transplantation in Germany. About three quarters of the variance remained unexplained, suggesting that factors not assessed or unknown may play a decisive role.

Item Type: Article
Uncontrolled Keywords: PANCREAS TRANSPLANTATION; DECISION-MAKING; KIDNEY; SURGEONS; MORTALITY; ACCEPT; Pancreas transplantation; Donor factors; Donor organ allocation
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Chirurgie
Medicine > Institut für Epidemiologie und Präventivmedizin > Medical Sociology
Depositing User: Dr. Gernot Deinzer
Date Deposited: 08 Aug 2019 07:10
Last Modified: 08 Aug 2019 07:10
URI: https://pred.uni-regensburg.de/id/eprint/9188

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