Drewitz, Karl Philipp and Loss, Martin and Loss, Julika and Apfelbacher, Christian Joachim (2014) Predictors of non-transplantation of adult donor organs - an observational study using routine data from Eurotransplant. BMC HEALTH SERVICES RESEARCH, 14: 584. ISSN 1472-6963,
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Background: The majority of pancreases, offered in allocation, are not transplanted. This pancreas under-utilisation is a phenomenon observed in all transplant systems in North-America and Europe. It was the aim of this study to analyse factors predictive of pancreas non-transplantation in Germany. Methods: Routine Eurotransplant data of 3,666 deceased German donors (from 2002-2011) were used for multivariate modelling. Socio-demographic and medical factors were considered as independent variables in logistic regression models with non-transplantation as dependent variable. Results: Male gender, advanced age, overweight/obesity, long ICU stay, a history of smoking, non-traumatic brain death, elevated levels of sodium, serum glucose, lipase/amylase and the liver not being considered for procurement were significant independent predictors of non-transplantation. Conclusion: In line with previous research, advanced age, high BMI, long ICU stay and the liver not being considered for procurement were the strongest predictors of pancreas non-transplantation in Germany. About three quarters of the variance remained unexplained, suggesting that factors not assessed or unknown may play a decisive role.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | PANCREAS TRANSPLANTATION; DECISION-MAKING; KIDNEY; SURGEONS; MORTALITY; ACCEPT; Pancreas transplantation; Donor factors; Donor organ allocation |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Chirurgie Medicine > Institut für Epidemiologie und Präventivmedizin > Medical Sociology |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 08 Aug 2019 07:10 |
| Last Modified: | 08 Aug 2019 07:10 |
| URI: | https://pred.uni-regensburg.de/id/eprint/9188 |
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