Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS)

Lefaucheur, Jean-Pascal and Andre-Obadia, Nathalie and Antal, Andrea and Ayache, Samar S. and Baeken, Chris and Benninger, David H. and Cantello, Roberto M. and Cincotta, Massimo and de Carvalho, Mamede and De Ridder, Dirk and Devanne, Herve and Di Lazzaro, Vincenzo and Filipovic, Sasa R. and Hummel, Friedhelm C. and Jaaskelainen, Satu K. and Kimiskidis, Vasilios K. and Koch, Giacomo and Langguth, Berthold and Nyffeler, Thomas and Oliviero, Antonio and Padberg, Frank and Poulet, Emmanuel and Rossi, Simone and Rossini, Paolo Maria and Rothwell, John C. and Schonfeldt-Lecuona, Carlos and Siebner, Hartwig R. and Slotema, Christina W. and Stagg, Charlotte J. and Valls-Sole, Josep and Ziemann, Ulf and Paulus, Walter and Garcia-Larrea, Luis (2014) Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS). CLINICAL NEUROPHYSIOLOGY, 125 (11). pp. 2150-2206. ISSN 1388-2457, 1872-8952

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Abstract

A group of European experts was commissioned to establish guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS) from evidence published up until March 2014, regarding pain, movement disorders, stroke, amyotrophic lateral sclerosis, multiple sclerosis, epilepsy, consciousness disorders, tinnitus, depression, anxiety disorders, obsessive-compulsive disorder, schizophrenia, craving/addiction, and conversion. Despite unavoidable inhomogeneities, there is a sufficient body of evidence to accept with level A (definite efficacy) the analgesic effect of high-frequency (HF) rTMS of the primary motor cortex (M1) contralateral to the pain and the antidepressant effect of HF-rTMS of the left dorsolateral prefrontal cortex (DLPFC). A Level B recommendation (probable efficacy) is proposed for the antidepressant effect of low-frequency (LF) rTMS of the right DLPFC, HF-rTMS of the left DLPFC for the negative symptoms of schizophrenia, and LF-rTMS of contralesional M1 in chronic motor stroke. The effects of rTMS in a number of indications reach level C (possible efficacy), including LF-rTMS of the left temporoparietal cortex in tinnitus and auditory hallucinations. It remains to determine how to optimize rTMS protocols and techniques to give them relevance in routine clinical practice. In addition, professionals carrying out rTMS protocols should undergo rigorous training to ensure the quality of the technical realization, guarantee the proper care of patients, and maximize the chances of success. Under these conditions, the therapeutic use of rTMS should be able to develop in the coming years. (C) 2014 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

Item Type: Article
Uncontrolled Keywords: DORSOLATERAL PREFRONTAL CORTEX; THETA-BURST STIMULATION; LOW-FREQUENCY RTMS; OBSESSIVE-COMPULSIVE DISORDER; PRIMARY MOTOR CORTEX; SHAM-CONTROLLED-TRIAL; NONINVASIVE BRAIN-STIMULATION; MAJOR DEPRESSIVE DISORDER; UPPER-LIMB HEMIPARESIS; DOUBLE-CONE COIL; Cortex; Indication; Neurological disease; Neuromodulation; Noninvasive brain stimulation; Psychiatric disease; TMS; Treatment
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Psychiatrie und Psychotherapie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 08 Aug 2019 08:23
Last Modified: 08 Aug 2019 08:23
URI: https://pred.uni-regensburg.de/id/eprint/9253

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