Jockenhoefer, F. and Gollnick, H. and Herberger, K. and Isbary, G. and Renner, R. and Stuecker, M. and Valesky, E. and Wollina, U. and Weichenthal, M. and Karrer, S. and Ross, B. and von Heinegg, E. Heintschel and Dissemond, J. (2014) Current detection rates of multiresistant gramnegative bacteria (3MRGN, 4MRGN) in patients with chronic leg ulcers. HAUTARZT, 65 (11). pp. 967-973. ISSN 0017-8470, 1432-1173
Full text not available from this repository. (Request a copy)Abstract
Due to the increasing problem of antibiotic resistance in gram-negative pathogens, the Commission for Hospital Hygiene and Infection Prevention (KRINKO) decided to establish a new clinically oriented definition of multi-resistance. Gram-negative pathogens with a multidrug-resistance (MRGN) are divided into those with resistance to three (3MRGN) or four (4MRGN) antibiotic groups. In this multicenter study which was done in ten dermatological wound clinics, the bacteriological swabs from up to 100 patients with chronic leg ulcers per center were analyzed according to the current classification KRINKO and evaluated. Overall, the results of 970 patients (553 women, 417 men) could be evaluated. We found 681 gram-positive and 1155 gram-negative bacteria. Pseudomonas aeruginosa was with a detection-rate of 31.1 % the most frequent gram-negative pathogen, followed by Proteus mirabilis with 13.7 % and various enterobacteria with 28.6 %. According to the current KRINKO classification,eight patients with 4MRGN and 34 patients with 3MRGN could be identified. Our results demonstrate the current spectrum of bacteria in patients with chronic leg ulcers with a variety of gram-negative pathogens, some of which are classified as multi-drug resistant. As a clinical consequence some of the patients require individualized preventive measures and therapy.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ANTIMICROBIAL RESISTANCE; BETA-LACTAMASES; SURVEILLANCE; MICROBIOLOGY; COLONIZATION; ENTEROBACTER; DERMATOLOGY; PATHOGENS; Chronic wound; Pseudomonas aeruginosa; Antibiotic; Robert Koch Institute; Prevention |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Dermatologie und Venerologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 08 Aug 2019 11:31 |
| Last Modified: | 08 Aug 2019 11:31 |
| URI: | https://pred.uni-regensburg.de/id/eprint/9269 |
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