Vaddepalli, Prasad and Herrmann, Anja and Fulton, Lynette and Oelschner, Maxi and Hillmer, Stefan and Stratil, Thomas F. and Fastner, Astrid and Hammes, Ulrich Z. and Ott, Thomas and Robinson, David G. and Schneitz, Kay (2014) The C2-domain protein QUIRKY and the receptor-like kinase STRUBBELIG localize to plasmodesmata and mediate tissue morphogenesis in Arabidopsis thaliana. DEVELOPMENT, 141 (21). pp. 4139-4148. ISSN 0950-1991, 1477-9129
Full text not available from this repository. (Request a copy)Abstract
Tissue morphogenesis in plants requires communication between cells, a process involving the trafficking of molecules through plasmodesmata (PD). PD conductivity is regulated by endogenous and exogenous signals. However, the underlying signaling mechanisms remain enigmatic. In Arabidopsis, signal transduction mediated by the receptor-like kinase STRUBBELIG (SUB) contributes to inter-cell layer signaling during tissue morphogenesis. Previous analysis has revealed that SUB acts non-cell-autonomously suggesting that SUB controls tissue morphogenesis by participating in the formation or propagation of a downstream mobile signal. A genetic screen identified QUIRKY(QKY), encoding a predicted membrane-anchored C2-domain protein, as a component of SUB signaling. Here, we provide further insight into the role of QKY in this process. We show that like SUB, QKY exhibits non-cell-autonomy when expressed in a tissue-specific manner and that non-autonomy of QKY extends across several cells. In addition, we report on localization studies indicating that QKY and SUB localize to PD but independently of each other. FRET-FLIM analysis suggests that SUB and QKY are in close contact at PD in vivo. We propose a model where SUB and QKY interact at PD to promote tissue morphogenesis, thereby linking RLK-dependent signal transduction and intercellular communication mediated by PD.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | EPIDERMAL-CELL DIFFERENTIATION; OVULE DEVELOPMENT; ROOT EPIDERMIS; SUBCELLULAR-LOCALIZATION; PATTERN-FORMATION; SHOOT MERISTEM; MOVEMENT; GENES; TRANSCRIPTION; EXPRESSION; Arabidopsis; Plasmodesmata; Signal transduction; Tissue morphogenesis; Receptor-like kinase; STRUBBELIG; QUIRKY |
| Subjects: | 500 Science > 580 Botanical sciences |
| Divisions: | Biology, Preclinical Medicine > Institut für Pflanzenwissenschaften > Lehrstuhl für Zellbiologie und Pflanzenphysiologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 09 Aug 2019 11:35 |
| Last Modified: | 09 Aug 2019 11:35 |
| URI: | https://pred.uni-regensburg.de/id/eprint/9319 |
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