Hehr, U. and Schoenbuchner, I. and Weber, B. H. F. (2014) Human genetic diagnostics in gynecological practice. GEBURTSHILFE UND FRAUENHEILKUNDE, 74 (10). R55-R73. ISSN 0016-5751, 1438-8804
Full text not available from this repository.Abstract
Diagnostic genetic studies support in gynecological practice interdisciplinary differential diagnostic clarification of existing clinical symptoms, especially in pregnancy and in the phase of family planning, but also in case of suspected hereditary cancer syndromes or other specific gynecological problems. If the family has a disease-causing genetic modification is already known or suspected disease risks in the context of genetic counseling with close relatives are discussed - including the offer to perform a predictive genetic test to the predisposition and the own risk of the disease or the offspring be clarified. To cause genetic tests to perform and communicate the findings regulated in Germany by Gendiagnostikgesetz. In this overview, important genetic analysis methods are introduced with their possibilities and limitations. Based on specific issues from the gynecological practice diagnostic algorithms, and in particular the importance of genetic findings raised for further patient care are discussed. In the future, new genetic test method, a much broader analysis on genetic characteristics allow. Their placing in the routine diagnosis frequent gynecological problems should be evidence-based and, if possible interdisciplinary principles indication-related recommendations.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | OVARIAN-CANCER; LYNCH-SYNDROME; BREAST-CANCER; HEREDITARY BREAST; SHORT VERSION; GUIDELINES; MANAGEMENT; GENOME; RISK; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Humangenetik |
| Depositing User: | Petra Gürster |
| Date Deposited: | 07 Aug 2020 06:39 |
| Last Modified: | 07 Aug 2020 06:39 |
| URI: | https://pred.uni-regensburg.de/id/eprint/9376 |
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