Galea, L. A. M. and Leuner, B. and Slattery, D. A. (2014) Hippocampal Plasticity during the Peripartum Period: Influence of Sex Steroids, Stress and Ageing. JOURNAL OF NEUROENDOCRINOLOGY, 26 (10). pp. 641-648. ISSN 0953-8194, 1365-2826
Full text not available from this repository. (Request a copy)Abstract
The peripartum period is accompanied by dramatic changes in hormones and a host of new behaviours in response to experience with offspring. Both maternal experience and maternal hormones can have a significant impact upon the brain and behaviour. This review outlines recent studies demonstrating modifications in hippocampal plasticity across the peripartum period, as well as the putative hormonal mechanisms underlying these changes and their modulation by stress. In addition, the impact of reproductive experience upon the ageing hippocampus is discussed. Finally, we consider how these changes in hippocampal structure may play a role in postpartum cognitive function and mood disorders, as well as age-related cognitive decline.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | CHRONIC RESTRAINT STRESS; PITUITARY-ADRENAL AXIS; CA3 PYRAMIDAL NEURONS; ADULT FEMALE RATS; CELL-PROLIFERATION; ALZHEIMERS-DISEASE; REPRODUCTIVE EXPERIENCE; POSTPARTUM DEPRESSION; MATERNAL-BEHAVIOR; SPATIAL MEMORY; lactation; postpartum; neurogenesis; corticosterone; cognition; depression |
| Subjects: | 500 Science > 570 Life sciences 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Biology, Preclinical Medicine > Institut für Zoologie > Tierphysiologie/Neurobiologie (Prof. Dr. Inga Neumann) |
| Depositing User: | Petra Gürster |
| Date Deposited: | 07 Aug 2020 06:17 |
| Last Modified: | 07 Aug 2020 06:17 |
| URI: | https://pred.uni-regensburg.de/id/eprint/9400 |
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