Elongator and SPT4/SPT5 complexes as proxy to study RNA polymerase II transcript elongation control of plant development

Van Lijsebettens, Mieke and Duerr, Julius and Woloszynska, Magdalena and Grasser, Klaus D. (2014) Elongator and SPT4/SPT5 complexes as proxy to study RNA polymerase II transcript elongation control of plant development. PROTEOMICS, 14 (19). pp. 2109-2114. ISSN 1615-9853, 1615-9861

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Abstract

The elongation phase of the RNA polymerase II (RNAPII) transcription process is dynamic and regulated. Elongator and SUPPRESSOR OF Ty4 (SPT4)/SPT5 are transcript elongation factors that contribute to the regulation of mRNA synthesis by RNA polymerase II in the chromatin context. Recently, the Elongator complex consisting of six subunits and the SPT4/SPT5 heterodimer were isolated from Arabidopsis. Mutant plants affected in the expression of Elongator or SPT4/SPT5 share various auxin-signaling phenotypes. In line with that observation, auxin-related genes are prominent among the genes differentially expressed in these mutants. Exemplified by Elongator and SPT4/SPT5, we discuss here the role that transcript elongation factors may play in the control of plant growth and development.

Item Type: Article
Uncontrolled Keywords: ARABIDOPSIS-THALIANA; SACCHAROMYCES-CEREVISIAE; HISTONE ACETYLTRANSFERASE; SEED DORMANCY; EXPRESSION; SUBUNIT; CYCLE; SPT4; PROCESSIVITY; GROWTH; Affinity purification; Arabidopsis; Auxin; Histone acetylation; Plant proteomics; Protein interaction
Subjects: 500 Science > 580 Botanical sciences
Divisions: Biology, Preclinical Medicine > Institut für Pflanzenwissenschaften > Lehrstuhl für Zellbiologie und Pflanzenphysiologie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 13 Aug 2019 08:59
Last Modified: 13 Aug 2019 08:59
URI: https://pred.uni-regensburg.de/id/eprint/9470

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