Comparison of Cardiogoniometry and ECG at Rest versus Myocardial Perfusion Scintigraphy

Weber, Stefan and Birkemeyer, Ralf and Schultes, Dominik and Grewenig, Walter and Huebner, Thomas (2014) Comparison of Cardiogoniometry and ECG at Rest versus Myocardial Perfusion Scintigraphy. ANNALS OF NONINVASIVE ELECTROCARDIOLOGY, 19 (5). pp. 462-470. ISSN 1082-720X, 1542-474X

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Abstract

BackgroundCardiogoniometry (CGM) is a novel resting electrocardiac method based on computer-generated three-dimensional data derived from cardiac potentials. The purpose of this study was to determine CGM's and electrocardiography's (ECG) accuracy for detecting myocardial ischemia and/or lesions in comparison with stress/rest myocardial perfusion scintigraphy (single photon emission computer tomography [SPECT]). MethodA cohort of consecutively enrolled patients (n = 100) with suspected or known coronary artery disease (mean age 67.8 years, 52% female) were examined by CGM and resting ECG before stress/rest myocardial scintigraphy. ResultsPathological scintigraphy findings at adenosine stress perfusion (ASP) and/or rest were conclusively identified in 21 patients. Diagnostic sensitivity was 71% for CGM and 24% for ECG, specificity was 70% for CGM and 95% for ECG. Reversible ischemia was diagnosed in 16 of 21 patients with pathological scintigraphy results. In this subgroup, sensitivity was 67% for CGM and 25% for ECG. ConclusionsAt rest, the sensitivity of a CGM significantly surmounts that of a standard 12-lead ECG for detection of isolated myocardial ischemia or myocardial lesions revealed by scintigraphy/SPECT; specificity is in a reasonable range. CGM's ease of use and its considerable agreement with the results of myocardial scintigraphy, suggests a possible role for patient screening in the primary care setting.

Item Type: Article
Uncontrolled Keywords: CORONARY-ARTERY-DISEASE; ELECTROCARDIOGRAM; VECTORCARDIOGRAM; INFARCTION; REPOLARIZATION; DIAGNOSIS; 12-LEAD; myocardial scar; coronary artery disease (CAD); patient management; vectorcardiography; risk stratification
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Innere Medizin II
Depositing User: Dr. Gernot Deinzer
Date Deposited: 27 Aug 2019 11:43
Last Modified: 27 Aug 2019 11:43
URI: https://pred.uni-regensburg.de/id/eprint/9624

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