Hutchinson, James A. and Ahrens, Norbert and Riquelme, Paloma and Walter, Lisa and Gruber, Michael and Boeger, Carsten A. and Farkas, Stefan and Scherer, Marcus N. and Broichhausen, Christiane and Bein, Thomas and Schlitt, Hans-J. and Faendrich, Fred and Banas, Bernhard and Geissler, Edward K. (2014) Clinical management of patients receiving cell-based immunoregulatory therapy. TRANSFUSION, 54 (9). pp. 2336-2343. ISSN 0041-1132, 1537-2995
Full text not available from this repository. (Request a copy)Abstract
Administering immunoregulatory cells as medicinal agents is a revolutionary approach to the treatment of immunologically mediated diseases. Isolating, propagating, and modifying cells before applying them to patients allows complementation of specific cellular functions, which opens astonishing new possibilities for gain-of-function antigen-specific treatments in autoimmunity, chronic inflammatory disorders, and transplantation. This critical review presents a systematic assessment of the potential clinical risks posed by cell-based immunotherapy, focusing on treatment of renal transplant recipients with regulatory macrophages as a concrete example.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | HUMAN REGULATORY MACROPHAGES; ACCEPTANCE-INDUCING-CELLS; T-CELLS; BLOOD-TRANSFUSION; TRANSPLANT RECIPIENTS; RENAL-TRANSPLANTATION; ALLOGRAFT SURVIVAL; FOXP3 EXPRESSION; PULMONARY; LUNG; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Anästhesiologie Medicine > Lehrstuhl für Chirurgie Medicine > Abteilung für Nephrologie Medicine > Lehrstuhl für Klinische Chemie und Laboratoriumsmedizin |
| Depositing User: | Petra Gürster |
| Date Deposited: | 04 Aug 2020 09:57 |
| Last Modified: | 04 Aug 2020 09:57 |
| URI: | https://pred.uni-regensburg.de/id/eprint/9644 |
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