Dye-Labeled C-alpha-Tetrasubstituted alpha-Amino Acids

Dobmeier, Michael and Maity, Prantik and Koenig, Burkhard (2014) Dye-Labeled C-alpha-Tetrasubstituted alpha-Amino Acids. HELVETICA CHIMICA ACTA, 97 (8). pp. 1061-1075. ISSN 0018-019X, 1522-2675

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Abstract

We report the synthesis of pyrene- and carboxyfluorescein labeled C-alpha-tetrasubstituted amino acids (TAAs). The fluorescent dye can be coupled to the TAA before or after its incorporation into a peptide sequence using a Suzuki-type C C bond formation.

Item Type: Article
Uncontrolled Keywords: CROSS-COUPLING REACTION; FLUORESCENT LIGANDS; EFFICIENT SYNTHESIS; BINDING DOMAIN; HECK REACTION; NK2 RECEPTOR; SIDE-CHAINS; PEPTIDES; DESIGN; PEPTIDOMIMETICS;
Subjects: 500 Science > 540 Chemistry & allied sciences
Divisions: Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König
Depositing User: Dr. Gernot Deinzer
Date Deposited: 04 Sep 2019 09:19
Last Modified: 04 Sep 2019 09:19
URI: https://pred.uni-regensburg.de/id/eprint/9782

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