RNA Binding of PRC2: Promiscuous or Well Ordered?

Kretz, Markus and Meister, Gunter (2014) RNA Binding of PRC2: Promiscuous or Well Ordered? MOLECULAR CELL, 55 (2). pp. 157-158. ISSN 1097-2765, 1097-4164

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Abstract

The polycomb repressive complex 2 (PRC2) methylates histones for epigenetic silencing and associates with thousands of protein-coding and noncoding RNAs. How the recruitment of PRC2 to specific sites is facilitated is currently unclear. Two recent studies have deciphered the impact of RNA binding on PRC2 recruitment and activity (Cifuentes-Rojas et al., 2014; Davidovich et al., 2013).

Item Type: Article
Uncontrolled Keywords: GENE-EXPRESSION; NONCODING RNAS; POLYCOMB; PROTEINS;
Subjects: 500 Science > 540 Chemistry & allied sciences
Divisions: Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Biochemie I
Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Biochemie I > Prof. Dr. Gunter Meister
Depositing User: Dr. Gernot Deinzer
Date Deposited: 06 Dec 2019 09:56
Last Modified: 06 Dec 2019 09:56
URI: https://pred.uni-regensburg.de/id/eprint/9871

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