Items where Author is "Lehle, Ludwig"
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Buettner, Falk F. R. and Ashikov, Angel and Tiemann, Birgit and Lehle, Ludwig and Bakker, Hans (2013) C. elegans DPY-19 Is a C-Mannosyltransferase Glycosylating Thrombospondin Repeats. MOLECULAR CELL, 50 (2). pp. 295-302. ISSN 1097-2765
Berends, Elsa and Lehle, Ludwig and Henquet, Maurice and Hesselink, Thamara and Woesten, Han A. B. and Lugones, Luis G. and Bosch, Dirk (2013) Identification of alg3 in the mushroom-forming fungus Schizophyllum commune and analysis of the Delta alg3 knockout mutant. GLYCOBIOLOGY, 23 (2). pp. 147-154. ISSN 0959-6658
Morava, Eva and Vodopiutz, Julia and Lefeber, Dirk J. and Janecke, Andreas R. and Schmidt, Wolfgang M. and Lechner, Silvia and Item, Chike B. and Sykut-Cegielska, Jolanta and Adamowicz, Maciej and Wierzba, Jolanta and Zhang, Zong H. and Mihalek, Ivana and Stockler, Sylvia and Bodamer, Olaf A. and Lehle, Ludwig and Wevers, Ron A. (2012) Defining the Phenotype in Congenital Disorder of Glycosylation Due to ALG1 Mutations. PEDIATRICS, 130 (4). E1034-E1039. ISSN 0031-4005
Timal, Sharita and Hoischen, Alexander and Lehle, Ludwig and Adamowicz, Maciej and Huijben, Karin and Sykut-Cegielska, Jolanta and Paprocka, Justyna and Jamroz, Ewa and van Spronsen, Francjan J. and Koerner, Christian and Gilissen, Christian and Rodenburg, Richard J. and Eidhof, Ilse and Van den Heuvel, Lambert and Thiel, Christian and Wevers, Ron A. and Morava, Eva and Veltman, Joris and Lefeber, Dirk J. (2012) Gene identification in the congenital disorders of glycosylation type I by whole-exome sequencing. HUMAN MOLECULAR GENETICS, 21 (19). pp. 4151-4161. ISSN 0964-6906
Tanner, Widmar and Lehle, Ludwig (2012) More than 40 years of glycobiology in Regensburg. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 425 (3). pp. 578-582. ISSN 0006-291X, 1090-2104
Pasikowska, Monika and Palamarczyk, Grazyna and Lehle, Ludwig (2012) The essential endoplasmic reticulum chaperone Rot1 is required for protein N- and O-glycosylation in yeast. GLYCOBIOLOGY, 22 (7). pp. 939-947. ISSN 0959-6658
Lefeber, Dirk J. and de Brouwer, Arjan P. M. and Morava, Eva and Riemersma, Moniek and Schuurs-Hoeijmakers, Janneke H. M. and Absmanner, Birgit and Verrijp, Kiek and van den Akker, Willem M. R. and Huijben, Karin and Steenbergen, Gerry and van Reeuwijk, Jeroen and Jozwiak, Adam and Zucker, Nili and Lorber, Avraham and Lammens, Martin and Knopf, Carlos and van Bokhoven, Hans and Gruenewald, Stephanie and Lehle, Ludwig and Kapusta, Livia and Mandel, Hanna and Wevers, Ron A. (2011) Autosomal Recessive Dilated Cardiomyopathy due to DOLK Mutations Results from Abnormal Dystroglycan O-Mannosylation. PLOS GENETICS, 7 (12): e1002427. ISSN 1553-7404
Absmanner, Birgit and Schmeiser, Verena and Kaempf, Michael and Lehle, Ludwig (2010) Biochemical characterization, membrane association and identification of amino acids essential for the function of Alg11 from Saccharomyces cerevisiae, an alpha 1,2-mannosyltransferase catalysing two sequential glycosylation steps in the formation of the lipid-linked core oligosaccharide. BIOCHEMICAL JOURNAL, 426. pp. 205-217. ISSN 0264-6021, 1470-8728
Cantagrel, Vincent and Lefeber, Dirk J. and Ng, Bobby G. and Guan, Ziqiang and Silhavy, Jennifer L. and Bielas, Stephanie L. and Lehle, Ludwig and Hombauer, Hans and Adamowicz, Maciej and Swiezewska, Ewa and De Brouwer, Arjan P. and Bluemel, Peter and Sykut-Cegielska, Jolanta and Houliston, Scott and Swistun, Dominika and Ali, Bassam R. and Dobyns, William B. and Babovic-Vuksanovic, Dusica and van Bokhoven, Hans and Wevers, Ron A. and Raetz, Christian R. H. and Freeze, Hudson H. and Morava, Eva and Al-Gazali, Lihadh and Gleeson, Joseph G. (2010) SRD5A3 Is Required for Converting Polyprenol to Dolichol and Is Mutated in a Congenital Glycosylation Disorder. CELL, 142 (2). pp. 203-217. ISSN 0092-8674, 1097-4172
Morava, Eva and Wevers, Ron A. and Cantagrel, Vincent and Hoefsloot, Lies H. and Al-Gazali, Lihadh and Schoots, Jeroen and van Rooij, Arno and Huijben, Karin and van Ravenswaaij-Arts, Connie M. A. and Jongmans, Marjolein C. J. and Sykut-Cegielska, Jolanta and Hoffmann, Georg F. and Bluemel, Peter and Adamowicz, Maciej and van Reeuwijk, Jeroen and Ng, Bobby G. and Bergman, Jorieke E. H. and van Bokhoven, Hans and Koerner, Christian and Babovic-Vuksanovic, Dusica and Willemsen, Michel A. and Gleeson, Joseph G. and Lehle, Ludwig and de Brouwer, Arjan P. M. and Lefeber, Dirk J. (2010) A novel cerebello-ocular syndrome with abnormal glycosylation due to abnormalities in dolichol metabolism. BRAIN, 133. pp. 3210-3220. ISSN 0006-8950
Rind, Nina and Schmeiser, Verena and Thiel, Christian and Absmanner, Birgit and Luebbehusen, Juergen and Hocks, Julia and Apeshiotis, Neophytos and Wilichowski, Ekkehard and Lehle, Ludwig and Koerner, Christian (2010) A severe human metabolic disease caused by deficiency of the endoplasmatic mannosyltransferase hALG11 leads to congenital disorder of glycosylation-Ip. HUMAN MOLECULAR GENETICS, 19 (8). pp. 1413-1424. ISSN 0964-6906, 1460-2083
Kaempf, Michael and Absmanner, Birgit and Schwarz, Markus and Lehle, Ludwig (2009) Biochemical Characterization and Membrane Topology of Alg2 from Saccharomyces cerevisiae as a Bifunctional alpha 1,3-and 1,6-Mannosyltransferase Involved in Lipid-linked Oligosaccharide Biosynthesis. JOURNAL OF BIOLOGICAL CHEMISTRY, 284 (18). pp. 11900-11912. ISSN 0021-9258, 1083-351X
Lefeber, Dirk J. and Schoenberger, Johannes and Morava, Eva and Guillard, Mailys and Huyben, Karin M. and Verriip, Kiek and Grafakou, Olga and Evangelioi, Athanasios and Preijers, Frank W. and Manta, Panagiota and Yildiz, Jef and Gruenewald, Stephanie and Spilioti, Martha and van den Elzen, Christa and Klein, Dominique and Hess, Daniel and Ashida, Hisashi and Hofsteenge, Jan and Maeda, Yusuke and van den Heuvel, Lambert and Lammens, Martin and Lehle, Ludwig and Wevers, Ron A. (2009) Deficiency of Dol-P-Man Synthase Subunit DPM3 Bridges the Congenital Disorders of Glycosylation with the Dystroglycanopathies. AMERICAN JOURNAL OF HUMAN GENETICS, 85 (1). pp. 76-86. ISSN 0002-9297, 1537-6605
Hese, Katrin and Otto, Claudia and Routier, Francoise H. and Lehle, Ludwig (2009) The yeast oligosaccharyltransferase complex can be replaced by STT3 from Leishmania major. GLYCOBIOLOGY, 19 (2). pp. 160-171. ISSN 0959-6658, 1460-2423
Henquet, Maurice and Lehle, Ludwig and Schreuder, Marielle and Rouwendal, Gerard and Molthoff, Jos and Helsper, Johannes and van der Krol, Sander and Bosch, Dirk (2008) Identification of the gene encoding the alpha 1,3-mannosyltransferase (ALG3) in Arabidopsis and characterization of downstream N-glycan processing. PLANT CELL, 20 (6). pp. 1652-1664. ISSN 1040-4651
Hauptmann, Peter and Lehle, Ludwig (2008) Kex1 protease is involved in yeast cell death induced by defective N-glycosylation, acetic acid, and chronological aging. JOURNAL OF BIOLOGICAL CHEMISTRY, 283 (27). pp. 19151-19163. ISSN 0021-9258, 1083-351X
Hauptmann, Peter and Riel, Constanze and Kunz-Schughart, Leoni A. and Froehlich, Kai-Uwe and Madeo, Frank and Lehle, Ludwig (2006) Defects in N-glycosylation induce apoptosis in yeast. MOLECULAR MICROBIOLOGY, 59 (3). pp. 765-778. ISSN 0950-382X, 1365-2958
Ecker, M. and Deutzmann, Rainer and Lehle, Ludwig and Mrsa, V. and Tanner, Widmar (2006) Pir proteins of Saccharomyces cerevisiae are attached to beta-1,3-glucan by a new protein-carbohydrate linkage. JOURNAL OF BIOLOGICAL CHEMISTRY, 281 (17). pp. 11523-11529. ISSN 0021-9258, 1083-351X
Lehle, Ludwig and Strahl, Sabine and Tanner, Widmar (2006) Protein glycosylation, conserved from yeast to man: A model organism helps elucidate congenital human diseases. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 45 (41). pp. 6802-6818. ISSN 1433-7851, 1521-3773
Bickel, Tanja and Lehle, Ludwig and Schwarz, Markus and Aebi, M. and Jakob, C .A. (2005) Biosynthesis of lipid-linked oligosaccharides in Saccharomyces cerevisiae - Alg13p AND Alg14p form a complex required for the formation of GlcNAc(2)-PP-dolichol. JOURNAL OF BIOLOGICAL CHEMISTRY, 280 (41). pp. 34500-34506. ISSN 0021-9258, 1083-351X
Schwarz, Markus and Knauer, Roland and Lehle, Ludwig (2005) Yeast oligosaccharyltransferase consists of two functionally distinct sub-complexes, specified by either the Ost3p or Ost6p subunit. FEBS LETTERS, 579 (29). pp. 6564-6568. ISSN 1873-3468
Kranz, Christian and Denecke, Jonas and Lehle, Ludwig and Sohlbach, Kristina and Jeske, Stefanie and Meinhardt, Friedhelm and Rossi, Rainer and Gudowius, Sonja and Marquardt, Thorsten (2004) Congenital disorder of glycosylation type Ik (CDG-Ik): A defect of mannosyltransferase I. AMERICAN JOURNAL OF HUMAN GENETICS, 74 (3). pp. 545-551. ISSN 0002-9297, 1537-6605
Schwarz, Markus and Thiel, Christian and Luebbehusen, Juergen and Dorland, Bert and de Koning, Tom and von Figura, Kurt and Lehle, Ludwig and Koerner, Christian (2004) Deficiency of GDP-Man : GlcNAc(2)-PP-dolichol mannosyltransferase causes congenital disorder of glycosylation type Ik. AMERICAN JOURNAL OF HUMAN GENETICS, 74 (3). pp. 472-481. ISSN 0002-9297, 1537-6605
Janik, Anna and Sosnowska, Monika and Kruszewska, Joanna and Krotkiewski, Hubert and Lehle, Ludwig and Palamarczyk, Grazyna (2003) Overexpression of GDP-mannose pyrophosphorylase in Saccharomyces cerevisiae corrects defects in dolichol-linked saccharide formation and protein glycosylation. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1621 (1). pp. 22-30. ISSN 0304-4165
Knauss, Stefan and Rohrmeier, Thomas and Lehle, Ludwig (2003) The auxin-induced maize gene ZmSAUR2 encodes a short-lived nuclear protein expressed in elongating tissues. JOURNAL OF BIOLOGICAL CHEMISTRY, 278 (26). pp. 23936-23943. ISSN 0021-9258
Thiel, Christian and Schwarz, Markus and Peng, Jianhe and Grzmil, Michal and Hasilik, Martin and Braulke, Thomas and Kohlschuetter, Alfried and von Figura, Kurt and Lehle, Ludwig and Koerner, Christian (2003) A new type of congenital disorders of glycosylation (CDG-Ii) provides new insights into the early steps of dolichol-linked oligosaccharide biosynthesis. JOURNAL OF BIOLOGICAL CHEMISTRY, 278 (25). pp. 22498-22505. ISSN 0021-9258, 1083-351X
Thiel, Christian and Schwarz, Markus and Hasilik, Martin and Grieben, Ulrike and Hanefeld, Folker and Lehle, Ludwig and von Figura, Kurt and Koerner, Christian (2002) Deficiency of dolichyl-P-Man: Man(7)GlcNAc(2)-PP-dolichyl mannosyltransferase causes congenital disorder of glycosylation type Ig. BIOCHEMICAL JOURNAL, 367 (1). pp. 195-201. ISSN 0264-6021
Sharma, Chandra B. and Knauer, Roland and Lehle, Ludwig (2001) Biosynthesis of lipid-linked oligosaccharides in yeast: the ALG3 gene encodes the DoI-P-Man : Man(5)GlcNAc(2)-PP-DoI mannosyltransferase. BIOLOGICAL CHEMISTRY, 382 (2). pp. 321-328. ISSN 1431-6730
Schleip, Ingeborg and Heiss, Elke and Lehle, Ludwig (2001) The yeast SEC20 gene is required for N- and O-glycosylation in the Golgi - Evidence that impaired glycosylation does not correlate with the secretory defect. JOURNAL OF BIOLOGICAL CHEMISTRY, 276 (31). pp. 28751-28758. ISSN 0021-9258, 1083-351X
Koerner, Christian and Knauer, Roland and Stephani, Ulrich and Marquardt, Thorsten and Lehle, Ludwig and von Figura, Kurt (1999) Carbohydrate deficient glycoprotein syndrome type IV: deficiency of dolichyl-P-Man : Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase. EMBO JOURNAL, 18 (23). pp. 6816-6822. ISSN 0261-4189,
Mrsa, Vladimir and Ecker, Margit and Strahl-Bolsinger, Sabine and Nimtz, Manfred and Lehle, Ludwig and Tanner, Widmar (1999) Deletion of new covalently linked cell wall glycoproteins alters the electrophoretic mobility of phosphorylated wall components of Saccharomyces cerevisiae. JOURNAL OF BACTERIOLOGY, 181 (10). pp. 3076-3086. ISSN 0021-9193,
Knauer, Roland and Lehle, Ludwig (1999) The oligosaccharyltransferase complex from Saccharomyces cerevisiae - Isolation of the OST6 gene, its synthetic interaction with OST3, and analysis of the native complex. JOURNAL OF BIOLOGICAL CHEMISTRY, 274 (24). pp. 17249-17256. ISSN 0021-9258, 1083-351X
Knauer, Roland and Lehle, Ludwig (1999) The oligosaccharyltransferase complex from yeast. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1426 (2). pp. 259-273. ISSN 0304-4165, 1872-8006
Körner, Christian and Lehle, Ludwig and von Figura, Kurt (1998) Abnormal synthesis of mannose 1-phosphate derived carbohydrates in carbohydrate-deficient glycoprotein syndrome type I fibroblasts with phosphomannomutase deficiency. GLYCOBIOLOGY, 8 (2). pp. 165-171. ISSN 0959-6658, 1460-2423
Okorokov, Lev A. and Lehle, Ludwig (1998) Ca2+-ATPases of Saccharomyces cerevisiae: diversity and possible role in protein sorting. FEMS MICROBIOLOGY LETTERS, 162 (1). pp. 83-91. ISSN 0378-1097, 1574-6968
Körner, Christian and Lehle, Ludwig and von Figura, Kurt (1998) Carbohydrate-deficient glycoprotein syndrome type 1: correction of the glycosylation defect by deprivation of glucose or supplementation of mannose. GLYCOCONJUGATE JOURNAL, 15 (5). pp. 499-505. ISSN 0282-0080,
Körner, Christian and Knauer, Roland and Holzbach, Ulrike and Hanefeld, Folker and Lehle, Ludwig and von Figura, Kurt (1998) Carbohydrate-deficient glycoprotein syndrome type V: Deficiency of dolichyl-P-Glc : Man(9)GlcNAc(2)-PP-dolichyl glucosyltransferase. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 95 (22). pp. 13200-13205. ISSN 0027-8424
Rothe, Christine and Lehle, Ludwig (1998) Sorting of invertase signal peptide mutants in yeast dependent and independent on the signal-recognition particle. EUROPEAN JOURNAL OF BIOCHEMISTRY, 252 (1). pp. 16-24. ISSN 0014-2956
