Items where Author is "Spoerner, Michael"

Article

Girard, Eric and Lopes, Pedro and Spoerner, Michael and Dhaussy, Anne-Claire and Prange, Thierry and Kalbitzer, Hans Robert and Colloc'h, Nathalie (2024) High Pressure Promotes Binding of the Allosteric Inhibitor Zn²⁺-Cyclen in Crystals of Activated H-Ras. CHEMISTRY-A EUROPEAN JOURNAL, 30 (35). e202400304. ISSN 0947-6539, 1521-3765

Girard, Eric and Lopes, Pedro and Spoerner, Michael and Dhaussy, Anne-Claire and Prange, Thierry and Kalbitzer, Hans Robert and Colloc'h, Nathalie (2022) Equilibria between conformational states of the Ras oncogene protein revealed by high pressure crystallography. CHEMICAL SCIENCE, 13 (7). pp. 2001-2010. ISSN 2041-6520, 2041-6539

Spoerner, Michael and Karl, Matthias and Lopes, Pedro and Hoering, Marcus and Loeffel, Karoline and Nuehs, Andrea and Adelsberger, Joseph and Kremer, Werner and Kalbitzer, Hans Robert (2017) High pressure P-31 NMR spectroscopy on guanine nucleotides. JOURNAL OF BIOMOLECULAR NMR, 67 (1). pp. 1-13. ISSN 0925-2738, 1573-5001

Zeraik, Ana E. and Pereira, Humberto M. and Santos, Yuri V. and Brandao-Neto, Jose and Spoerner, Michael and Santos, Maiara S. and Colnago, Luiz A. and Garratt, Richard C. and Araujo, Ana P. U. and DeMarco, Ricardo (2014) Crystal Structure of a Schistosoma mansoni Septin Reveals the Phenomenon of Strand Slippage in Septins Dependent on the Nature of the Bound Nucleotide. JOURNAL OF BIOLOGICAL CHEMISTRY, 289 (11). pp. 7799-7811. ISSN 0021-9258, 1083-351X

Rosnizeck, Ina C. and Filchtinski, Daniel and Lopes, Rui Pedro and Kieninger, Baerbel and Herrmann, Christian and Kalbitzer, Hans Robert and Spoerner, Michael (2014) Elucidating the Mode of Action of a Typical Ras State 1(T) Inhibitor. BIOCHEMISTRY, 53 (24). pp. 3867-3878. ISSN 0006-2960

Kalbitzer, Hans Robert and Rosnizeck, Ina C. and Munte, Claudia E. and Narayanan, Sunilkumar Puthenpurackal and Kropf, Veronika and Spoerner, Michael (2013) Intrinsic Allosteric Inhibition of Signaling Proteins by Targeting Rare Interaction States Detected by High-Pressure NMR Spectroscopy. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 52 (52). pp. 14242-14246. ISSN 1433-7851, 1521-3773

Jank, Thomas and Bogdanovic, Xenia and Wirth, Christophe and Haaf, Erik and Spoerner, Michael and Boehmer, Kira E. and Steinemann, Marcus and Orth, Joachim H. C. and Kalbitzer, Hans Robert and Warscheid, Bettina and Hunte, Carola and Aktories, Klaus (2013) A bacterial toxin catalyzing tyrosine glycosylation of Rho and deamidation of G(q) and G(i) proteins. NATURE STRUCTURAL & MOLECULAR BIOLOGY, 20 (11). pp. 1273-1280. ISSN 1545-9993, 1545-9985

Spoerner, Michael and Wichard, Thomas and Bachhuber, Tanja and Stratmann, Johannes and Oertel, Wolfgang (2012) Growth and Thallus Morphogenesis of Ulva mutabilis (Chlorophyta) Depends on A Combination of Two Bacterial Species Excreting Regulatory Factors. JOURNAL OF PHYCOLOGY, 48 (6). pp. 1433-1447. ISSN 0022-3646, 1529-8817

Rosnizeck, Ina C. and Spoerner, Michael and Harsch, Tobias and Kreitner, Sandra and Filchtinski, Daniel and Herrmann, Christian and Engel, Daniel and Koenig, Burkhard and Kalbitzer, Hans Robert (2012) Metal-Bis(2-picolyl)amine Complexes as State 1(T) Inhibitors of Activated Ras Protein. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 51 (42). pp. 10647-10651. ISSN 1433-7851, 1521-3773

Meierhofer, Tanja and Eberhardt, Maren and Spoerner, Michael (2011) Conformational States of ADP Ribosylation Factor 1 Complexed with Different Guanosine Triphosphates As Studied by P-31 NMR Spectroscopy. BIOCHEMISTRY, 50 (29). pp. 6316-6327. ISSN 0006-2960

Meierhofer, Tanja and Rosnizeck, Ina C. and Graf, Thorsten and Reiss, Kerstin and Koenig, Burkhard and Kalbitzer, Hans Robert and Spoerner, Michael (2011) Cu(2+-)cyclen as Probe to Identify Conformational States in Guanine Nucleotide Binding Proteins. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 133 (7). pp. 2048-2051. ISSN 0002-7863

Sieber, Timo and Scholz, Roland and Spoerner, Michael and Schumann, Frank and Kalbitzer, Hans Robert and Dobner, Thomas (2011) Intrinsic disorder in the common N-terminus of human adenovirus 5 E1B-55K and its related E1BN proteins indicated by studies on E1B-93R. VIROLOGY, 418 (2). pp. 133-143. ISSN 0042-6822

Schmidt, Florian and Spoerner, Michael and Kalbitzer, Hans Robert and Koenig, Burkhard (2011) SYNTHESIS OF NEW WATER-SOLUBLE CHOLESTEROL DERIVATIVES. SYNTHETIC COMMUNICATIONS, 41 (19). pp. 2876-2887. ISSN 0039-7911

Schmidt, Florian and Rosnizeck, Ina C. and Spoerner, Michael and Kalbitzer, Hans Robert and Koenig, Burkhard (2011) Zinc(II)cyclen-peptide conjugates interacting with the weak effector binding state of Ras. INORGANICA CHIMICA ACTA, 365 (1). pp. 38-48. ISSN 0020-1693, 1873-3255

Spoerner, Michael and Hozsa, Constantin and Poetzl, Johann A. and Reiss, Kerstin and Ganser, Petra and Geyer, Matthias and Kalbitzer, Hans Robert (2010) Conformational States of Human Rat Sarcoma (Ras) Protein Complexed with Its Natural Ligand GTP and Their Role for Effector Interaction and GTP Hydrolysis. JOURNAL OF BIOLOGICAL CHEMISTRY, 285 (51). pp. 39768-39778. ISSN 0021-9258, 1083-351X

Rosnizeck, Ina C. and Graf, Thorsten and Spoerner, Michael and Traenkle, Jens and Filchtinski, Daniel and Herrmann, Christian and Gremer, Lothar and Vetter, Ingrid R. and Wittinghofer, Alfred and Koenig, Burkhard and Kalbitzer, Hans Robert (2010) Stabilizing a Weak Binding State for Effectors in the Human Ras Protein by Cyclen Complexes. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 49 (22). pp. 3830-3833. ISSN 1433-7851

Kalbitzer, Hans Robert and Spoerner, Michael and Ganser, Petra and Hozsa, Constantin and Kremer, Werner (2009) Fundamental Link between Folding States and Functional States of Proteins. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 131 (46). pp. 16714-16719. ISSN 0002-7863

Kiel, Christina and Filchtinski, Daniel and Spoerner, Michael and Schreiber, Gideon and Kalbitzer, Hans Robert and Herrmann, Christian (2009) Improved Binding of Raf to Ras.GDP Is Correlated with Biological Activity. JOURNAL OF BIOLOGICAL CHEMISTRY, 284 (46). pp. 31893-31902. ISSN 0021-9258, 1083-351X

Spoerner, Michael and Nuehs, Andrea and Herrmann, Christian and Steiner, Guido and Kalbitzer, Hans Robert (2007) Slow conformational dynamics of the guanine nucleotide-binding protein Ras complexed with the GTP analogue GTP gamma S. FEBS JOURNAL, 274 (6). pp. 1419-1433. ISSN 1742-464X, 1742-4658

Ader, Christian and Spoerner, Michael and Kalbitzer, Hans Robert and Brunner, Eike (2007) Solid-state P-31 NMR spectroscopy of precipitated guanine nucleotide-binding protein ras in complexes with its effector molecules raf kinase and RalGDS. JOURNAL OF PHYSICAL CHEMISTRY B, 111 (10). pp. 2752-2757. ISSN 1520-6106

Iuga, Adriana and Spoerner, Michael and Ader, Christian and Brunner, Eike and Kalbitzer, Hans Robert (2006) Rapid assignment of solution P-31 NMR spectra of large proteins by solid-state spectroscopy. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 346 (1). pp. 301-305. ISSN 0006-291X, 1090-2104

Spoerner, Michael and Nuehs, Andrea and Ganser, Petra and Herrmann, C. and Wittinghofer, A. and Kalbitzer, Hans Robert (2005) Conformational states of ras complexed with the GTP analogue GppNHp or GppCH(2)p: Implications for the interaction with effector proteins. BIOCHEMISTRY, 44 (6). pp. 2225-2236. ISSN 0006-2960

Spoerner, Michael and Wittinghofer, Alfred and Kalbitzer, Hans Robert (2004) Perturbation of the conformational equilibria in Ras by selective mutations as studied by P-31 NMR spectroscopy. FEBS LETTERS, 578 (3). pp. 305-310. ISSN 0014-5793

Iuga, Adriana and Spoerner, Michael and Kalbitzer, Hans Robert and Brunner, Eike (2004) Solid-state P-31 NMR spectroscopy of microcrystals of the Ras protein and its effector loop mutants: Comparison between crystalline and solution state. JOURNAL OF MOLECULAR BIOLOGY, 342 (3). pp. 1033-1040. ISSN 0022-2836, 1089-8638

Spoerner, Michael and Herrmann, Christian and Vetter, Ingrid R. and Kalbitzer, Hans Robert and Wittinghofer, Alfred (2001) Dynamic properties of the Ras switch I region and its importance for binding to effectors. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 98 (9). pp. 4944-4949. ISSN 0027-8424

Gronwald, Wolfram and Huber, Fritz and Gruenewald, Petra and Spoerner, Michael and Wohlgemuth, Sabine and Herrmann, Christian and Kalbitzer, Hans Robert (2001) Solution structure of the Ras binding domain of the protein kinase Byr2 from Schizosaccharomyces pombe. STRUCTURE, 9 (11). pp. 1029-1041. ISSN 0969-2126

Rohrer, Martin and Prisner, Thomas F. and Bruegmann, Oliver and Kaess, Hanno and Spoerner, Michael and Wittinghofer, Alfred and Kalbitzer, Hans Robert (2001) Structure of the metal-water complex in Ras center dot GDP studied by high-field EPR spectroscopy and P-31 NMR spectroscopy. BIOCHEMISTRY, 40 (7). pp. 1884-1889. ISSN 0006-2960

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Karl, Matthias and Spoerner, Michael and Thuy-Vy Pham, and Narayanan, Sunilkumar Puthenpurackal and Kremer, Werner and Kalbitzer, Hans Robert (2017) Pressure response of P-31 chemical shifts of adenine nucleotides. [["eprint_typename_proceedings" not defined]]