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A

Abstiens, Kathrin and Gregoritza, Manuel and Goepferich, Achim M. (2019) Ligand Density and Linker Length are Critical Factors for Multivalent Nanoparticle-Receptor Interactions. ACS APPLIED MATERIALS & INTERFACES, 11 (1). pp. 1311-1320. ISSN 1944-8244

Agnetta, Luca and Bermudez, Marcel and Riefolo, Fabio and Matera, Carlo and Claro, Enrique and Messerer, Regina and Littmann, Timo and Wolber, Gerhard and Holzgrabe, Ulrike and Decker, Michael (2019) Fluorination of Photoswitchable Muscarinic Agonists Tunes Receptor Pharmacology and Photochromic Properties. JOURNAL OF MEDICINAL CHEMISTRY, 62 (6). pp. 3009-3020. ISSN 0022-2623, 1520-4804

Apers, Sandra and Paper, Dietrich and Buergermeister, Jutta and Baronikova, Slavka and Van Dyck, Stefaan and Lemiere, Guy and Vlietinck, Arnold and Pieters, Luc (2002) Antiangiogenic activity of synthetic dihydrobenzofuran lignans. JOURNAL OF NATURAL PRODUCTS, 65 (5). pp. 718-720. ISSN 0163-3864

B

Bartole, Edith and Graetz, Lukas and Littmann, Timo and Wifling, David and Seibel, Ulla and Buschauer, Armin and Bernhardt, Guenther (2020) UR-DEBa242: A Py-5-Labeled Fluorescent Multipurpose Probe for Investigations on the Histamine H-3 and H-4 Receptors. JOURNAL OF MEDICINAL CHEMISTRY, 63 (10). pp. 5297-5311. ISSN 0022-2623, 1520-4804

Biselli, Sabrina and Alencastre, Ines and Tropmann, Katharina and Erdmann, Daniela and Chen, Mengya and Littmann, Timo and Maia, Andre F. and Gomez-Lazaro, Maria and Tanaka, Miho and Ozawa, Takeaki and Keller, Max and Lamghari, Meriem and Buschauer, Armin and Bernhardt, Guenther (2020) Fluorescent H-2 Receptor Squaramide-Type Antagonists: Synthesis, Characterization, and Applications. ACS MEDICINAL CHEMISTRY LETTERS, 11 (8). pp. 1521-1528. ISSN 1948-5875

Bresinsky, Merlin and Shahraki, Aida and Kolb, Peter and Pockes, Steffen and Schihada, Hannes (2023) Development of Fluorescent AF64394 Analogues Enables Real-Time Binding Studies for the Orphan Class A GPCR GPR3. JOURNAL OF MEDICINAL CHEMISTRY, 66 (21). pp. 15025-15041. ISSN 0022-2623, 1520-4804

C

Chen, Kang and Berg, Nele and Gschwind, Ruth and Koenig, Burkhard (2017) Selective Single C(sp(3))-F Bond Cleavage in Trifluoromethylarenes: Merging Visible-Light Catalysis with Lewis Acid Activation. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 139 (51). pp. 18444-18447. ISSN 0002-7863

Chen, Xinyu and Kloeckner, Jessika and Holze, Janine and Zimmermann, Cornelia and Seemann, Wiebke K. and Schrage, Ramona and Bock, Andreas and Mohr, Klaus and Traenkle, Christian and Holzgrabe, Ulrike and Decker, Michael (2015) Rational Design of Partial Agonists for the Muscarinic M-1 Acetylcholine Receptor. JOURNAL OF MEDICINAL CHEMISTRY, 58 (2). pp. 560-576. ISSN 0022-2623, 1520-4804

Cuboni, Serena and Devigny, Christian and Hoogeland, Bastiaan and Strasser, Andrea and Pomplun, Sebastian and Hauger, Barbara and Hoefner, Georg and Wanner, Klaus T. and Eder, Matthias and Buschauer, Armin and Holsboer, Florian and Hausch, Felix (2014) Loratadine and Analogues: Discovery and Preliminary Structure-Activity Relationship of Inhibitors of the Amino Acid Transporter B(0)AT2. JOURNAL OF MEDICINAL CHEMISTRY, 57 (22). pp. 9473-9479. ISSN 0022-2623, 1520-4804

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Darras, Fouad H. and Kling, Beata and Heilmann, Joerg and Decker, Michael (2012) Neuroprotective Tri- and Tetracyclic BChE Inhibitors Releasing Reversible Inhibitors upon Carbamate Transfer. ACS MEDICINAL CHEMISTRY LETTERS, 3 (11). pp. 914-919. ISSN 1948-5875

Dukorn, Stefanie and Littmann, Timo and Keller, Max and Kuhn, Kilian and Cabrele, Chiara and Baumeister, Paul and Bernhardt, Guenther and Buschauer, Armin (2017) Fluorescence- and Radiolabeling of [Lys(4),Nle(17,30)]hPP Yields Molecular Tools for the NPY Y-4 Receptor. BIOCONJUGATE CHEMISTRY, 28 (4). pp. 1291-1304. ISSN 1043-1802

E

Ertl, Fabian J. and Kopanchuk, Sergei and Dijon, Nicola C. and Veiksina, Santa and Tahk, Maris-Johanna and Laasfeld, Tonis and Schettler, Franziska and Gattor, Albert O. and Huebner, Harald and Archipowa, Nataliya and Koeckenberger, Johannes and Heinrich, Markus R. and Gmeiner, Peter and Kutta, Roger J. and Holliday, Nicholas D. and Rinken, Ago and Keller, Max (2024) Dually Labeled Neurotensin NTS1R Ligands for Probing Radiochemical and Fluorescence-Based Binding Assays. JOURNAL OF MEDICINAL CHEMISTRY, 67 (18). pp. 16664-16691. ISSN 0022-2623, 1520-4804

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Fleischmann, Daniel and Figueroa, Sara Maslanka and Beck, Sebastian and Abstiens, Kathrin and Witzgall, Ralph and Schweda, Frank and Tauber, Philipp and Goepferich, Achim (2020) Adenovirus-Mimetic Nanoparticles: Sequential Ligand-Receptor Interplay as a Universal Tool for Enhanced In Vitro/In Vivo Cell Identification. ACS APPLIED MATERIALS & INTERFACES, 12 (31). pp. 34689-34702. ISSN 1944-8244, 1944-8252

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Gastpar, Robert and Goldbrunner, Michael and Marko, Doris and von Angerer, Erwin (1998) Methoxy-substituted 3-formyl-2-phenylindoles inhibit tubulin polymerization. JOURNAL OF MEDICINAL CHEMISTRY, 41 (25). pp. 4965-4972. ISSN 0022-2623,

Gleixner, Jakob and Gattor, Albert O. and Humphrys, Laura J. and Brunner, Thomas and Keller, Max (2023) [<SUP>3</SUP>H]UR-JG102-A Radiolabeled Cyclic Peptide with High Affinity and Excellent Selectivity for the Neuropeptide Y Y₄ Receptor. JOURNAL OF MEDICINAL CHEMISTRY, 66 (19). pp. 13788-13808. ISSN 0022-2623, 1520-4804

Goldbrunner, Michael and Loidl, Günther and Polossek, Thomas and Mannschreck, Albrecht and von Angerer, Erwin (1997) Inhibition of tubulin polymerization by 5,6-dihydroindolo[2,1-a]isoquinoline derivatives. JOURNAL OF MEDICINAL CHEMISTRY, 40 (22). pp. 3524-3533. ISSN 0022-2623, 1520-4804

Gregoritza, Manuel and Messmann, Viktoria and Abstiens, Kathrin and Brandl, Ferdinand P. and Goepferich, Achim M. (2017) Controlled Antibody Release from Degradable Thermoresponsive Hydrogels Cross-Linked by Diets-Alder Chemistry. BIOMACROMOLECULES, 18 (8). pp. 2410-2418. ISSN 1525-7797, 1526-4602

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Karcz, Tadeusz and Szczepanska, Katarzyna and Mogilski, Szczepan and Moroz, Aleksandra and Olejarz-Maciej, Agnieszka and Humphrys, Laura J. and Pockes, Steffen and Siwek, Agata and Dubiel, Krzysztof and Staszewski, Marek and Calmels, Thierry and Waczynski, Krzysztof and Kiec-Kononowicz, Katarzyna (2024) Guanidine Derivative ADS1017, a Potent Histamine H3 Receptor Antagonist with Promising Analgesic Activity and Satisfactory Safety Profile. ACS CHEMICAL NEUROSCIENCE, 15 (24). pp. 4441-4457. ISSN 1948-7193

Keller, Max and Kuhn, Kilian K. and Einsiedel, Juergen and Huebner, Harald and Biselli, Sabrina and Mollereau, Catherine and Wifling, David and Svobodova, Jaroslava and Bernhardt, Guenther and Cabrele, Chiara and Vanderheyden, Patrick M. L. and Gmeiner, Peter and Buschauer, Armin (2016) Mimicking of Arginine by Functionalized N-omega-Carbamoylated Arginine As a New Broadly Applicable Approach to Labeled Bioactive Peptides: High Affinity Angiotensin, Neuropeptide Y, Neuropeptide FF, and Neurotensin Receptor Ligands As Examples. JOURNAL OF MEDICINAL CHEMISTRY, 59 (5). pp. 1925-1945. ISSN 0022-2623, 1520-4804

Keller, Max and Mahuroof, Shahani A. and Yee, Vivyanne Hong and Carpenter, Jessica and Schindler, Lisa and Littmann, Timo and Pegoli, Andrea and Huebner, Harald and Bernhardt, Guenther and Gmeiner, Peter and Holliday, Nicholas D. (2020) Fluorescence Labeling of Neurotensin(8-13) via Arginine Residues Gives Molecular Tools with High Receptor Affinity. ACS MEDICINAL CHEMISTRY LETTERS, 11 (1). pp. 16-22. ISSN 1948-5875

Keller, Max and Weiss, Stefan and Hutzler, Christoph and Kuhn, Kilian K. and Mollereau, Catherine and Dukorn, Stefanie and Schindler, Lisa and Bernhardt, Gunther and Konig, Burkhard and Buschauer, Armin (2015) N-omega-Carbamoylation of the Argininamide Moiety: An Avenue to Insurmountable NPY Y-1 Receptor Antagonists and a Radio labeled Selective High-Affinity Molecular Tool ([H-3]UR-MK299) with Extended Residence Time. JOURNAL OF MEDICINAL CHEMISTRY, 58 (22). pp. 8834-8849. ISSN 0022-2623, 1520-4804

Konieczny, Adam and Braun, Diana and Wifling, David and Bernhardt, Guenther and Keller, Max (2020) Oligopeptides as Neuropeptide Y Y-4 Receptor Ligands: Identification of a High-Affinity Tetrapeptide Agonist and a Hexapeptide Antagonist. JOURNAL OF MEDICINAL CHEMISTRY, 63 (15). pp. 8198-8215. ISSN 0022-2623, 1520-4804

Kratochwil, Nicole A. and Guo, Zijian and Murdoch, Piedad del Socorro and Parkinson, John A. and Bednarski, Patrick J. and Sadler, Peter J. (1998) Electron-transfer-driven trans-ligand labilization: A novel activation mechanism for Pt(IV) anticancer complexes. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 120 (32). pp. 8253-8254. ISSN 0002-7863, 1520-5126

Kratochwil, Nicole A. and Zabel, Manfred and Range, Klaus-Jürgen and Bednarski, Patrick J. (1996) Synthesis and X-ray crystal structure of trans,cis-[Pt(OAc)(2)I-2(en)]: A novel type of cisplatin analog that can be photolyzed by visible light to DNA-binding and cytotoxic species in vitro. JOURNAL OF MEDICINAL CHEMISTRY, 39 (13). pp. 2499-2507. ISSN 0022-2623, 1520-4804

Kuhn, Kilian K. and Ertl, Thomas and Dukorn, Stefanie and Keller, Max and Bernhardt, Guenther and Reiser, Oliver and Buschauer, Armin (2016) High Affinity Agonists of the Neuropeptide Y (NPY) Y-4 Receptor Derived from the C-Terminal Pentapeptide of Human Pancreatic Polypeptide (hPP): Synthesis, Stereochemical Discrimination, and Radiolabeling. JOURNAL OF MEDICINAL CHEMISTRY, 59 (13). pp. 6045-6058. ISSN 0022-2623, 1520-4804

Kuhn, Kilian K. and Littmann, Timo and Dukorn, Stefanie and Tanaka, Miho and Keller, Max and Ozawa, Takeaki and Bernhardt, Gunther and Buschauer, Armin (2017) In Search of NPY Y4R Antagonists: Incorporation of Carbamoylated Arginine, Aza-Amino Acids, or D-Amino Acids into Oligopeptides Derived from the C-Termini of the Endogenous Agonists. ACS OMEGA, 2 (7). pp. 3616-3631. ISSN 2470-1343

Kumar, Sunil and Mueller, Klaus (1999) Lichen metabolites. 1. Inhibitory action against leukotriene B-4 biosynthesis by a non-redox mechanism. JOURNAL OF NATURAL PRODUCTS, 62 (6). pp. 817-820. ISSN 0163-3864, 1520-6025

Kumar, Sunil and Mueller, Klaus (1999) Lichen metabolites. 2. Antiproliferative and cytotoxic activity of gyrophoric, usnic, and diffractaic acid on human keratinocyte growth. JOURNAL OF NATURAL PRODUCTS, 62 (6). pp. 821-823. ISSN 0163-3864, 1520-6025

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Lottner, Christian and Bart, Karl-Christian and Bernhardt, Guenther and Brunner, Henri (2002) Hematoporphyrin-derived soluble porphyrin-platinum conjugates with combined cytotoxic and phototoxic antitumor activity. JOURNAL OF MEDICINAL CHEMISTRY, 45 (10). pp. 2064-2078. ISSN 0022-2623, 1520-4804

Lottner, Christian and Bart, Karl-Christian and Bernhardt, Günther and Brunner, Henri (2002) Soluble tetraarylporphyrin-platinum conjugates as cytotoxic and phototoxic antitumor agents. JOURNAL OF MEDICINAL CHEMISTRY, 45 (10). pp. 2079-2089. ISSN 0022-2623

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Mahboobi, Siavosh and Dove, Stefan and Sellmer, Andreas and Winkler, Matthias and Eichhorn, Emerich and Pongratz, Herwig and Ciossek, Thomas and Baer, Thomas and Maier, Thomas and Beckers, Thomas (2009) Design of Chimeric Histone Deacetylase- and Tyrosine Kinase-Inhibitors: A Series of Imatinib Hybrides as Potent Inhibitors of Wild-Type and Mutant BCR-ABL, PDGF-R beta, and Histone Deacetylases. JOURNAL OF MEDICINAL CHEMISTRY, 52 (8). pp. 2265-2279. ISSN 0022-2623, 1520-4804

Mannschreck, Albrecht and Kiesswetter, Roland and von Angerer, Erwin (2007) Unequal activities of enantiomers via biological receptors: Examples of chiral drug, pesticide, and fragrance molecules. JOURNAL OF CHEMICAL EDUCATION, 84 (12). pp. 2012-2018. ISSN 0021-9584

Mannschreck, Albrecht and von Angerer, Erwin (2011) The Scent of Roses and Beyond: Molecular Structures, Analysis, and Practical Applications of Odorants. JOURNAL OF CHEMICAL EDUCATION, 88 (11). pp. 1501-1506. ISSN 0021-9584

Moennich, Denise and Nagl, Martin and Forster, Lisa and Rosier, Niklas and Igel, Patrick and Pockes, Steffen (2023) Discovery of a Tritiated Radioligand with High Affinity and Selectivity for the Histamine H3 Receptor. ACS MEDICINAL CHEMISTRY LETTERS, 14 (11). pp. 1589-1595. ISSN 1948-5875,

Mueller, Christoph and Gleixner, Jakob and Tahk, Maris-Johanna and Kopanchuk, Sergei and Laasfeld, Tonis and Weinhart, Michael and Schollmeyer, Dieter and Betschart, Martin U. and Luedeke, Steffen and Koch, Pierre and Rinken, Ago and Keller, Max (2022) Structure-Based Design of High-Affinity Fluorescent Probes for the Neuropeptide Y Y-1 Receptor. JOURNAL OF MEDICINAL CHEMISTRY, 65 (6). pp. 4832-4853. ISSN 0022-2623, 1520-4804

Murphy, Matthew B. and Hartgerink, Jeffrey D. and Goepferich, Achim and Mikos, Antonios G. (2007) Synthesis and in vitro hydroxyapatite binding of peptides conjugated to calcium-binding moieties. BIOMACROMOLECULES, 8 (7). pp. 2237-2243. ISSN 1525-7797

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Pegoli, Andrea and She, Xueke and Wifling, David and Huebner, Harald and Bernhardt, Guenther and Gmeiner, Peter and Keller, Max (2017) Radiolabeled Dibenzodiazepinone-Type Antagonists Give Evidence of Dualsteric Binding at the M-2 Muscarinic Acetylcholine Receptor. JOURNAL OF MEDICINAL CHEMISTRY, 60 (8). pp. 3314-3334. ISSN 0022-2623, 1520-4804

Pegoli, Andrea and Wifling, David and Gruber, Corinna G. and She, Xueke and Huebner, Harald and Bernhardt, Guenther and Gmeiner, Peter and Keller, Max (2019) Conjugation of Short Peptides to Dibenzodiazepinone-Type Muscarinic Acetylcholine Receptor Ligands Determines M2R Selectivity. JOURNAL OF MEDICINAL CHEMISTRY, 62 (11). pp. 5358-5369. ISSN 0022-2623, 1520-4804

Pena-Solorzano, Diana and Scholler, Matthias and Bernhardt, Guenther and Buschauer, Armin and Koenig, Burkhard and Ochoa-Puentes, Cristian (2018) Tariquidar-Related Chalcones and Ketones as ABCG2 Modulators. ACS MEDICINAL CHEMISTRY LETTERS, 9 (8). pp. 854-859. ISSN 1948-5875

Plut, Eva and Calderon, Jacqueline C. and Stanojlovic, Vesna and Gattor, Albert O. and Hoering, Carina and Humphrys, Laura J. and Konieczny, Adam and Kerres, Sabine and Schubert, Mario and Keller, Max and Cabrele, Chiara and Clark, Timothy and Reiser, Oliver (2023) Stereochemistry-Driven Interactions of α,γ-Peptide Ligands with the Neuropeptide Y Y4-Receptor. JOURNAL OF MEDICINAL CHEMISTRY, 66 (14). pp. 9642-9657. ISSN 0022-2623, 1520-4804

Pockes, Steffen and Wifling, David and Keller, Max and Buschauer, Armin and Elz, Sigurd (2018) Highly Potent, Stable, and Selective Dimeric Hetarylpropylguanidine-Type Histamine H-2 Receptor Agonists. ACS OMEGA, 3 (3). pp. 2865-2882. ISSN 2470-1343

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Rosier, Niklas and Graetz, Lukas and Schihada, Hannes and Moeller, Jan and Isbilir, Ali and Humphrys, Laura J. and Nagl, Martin and Seibel, Ulla and Lohse, Martin J. and Pockes, Steffen (2021) A Versatile Sub-Nanomolar Fluorescent Ligand Enables NanoBRET Binding Studies and Single-Molecule Microscopy at the Histamine H-3 Receptor. JOURNAL OF MEDICINAL CHEMISTRY, 64 (15). pp. 11695-11708. ISSN 0022-2623, 1520-4804

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Sawatzky, Edgar and Wehle, Sarah and Kling, Beata and Wendrich, Jan and Bringmann, Gerhard and Sotriffer, Christoph A. and Heilmann, Joerg and Decker, Michael (2016) Discovery of Highly Selective and Nanomolar Carbamate-Based Butyrylcholinesterase Inhibitors by Rational Investigation into Their Inhibition Mode. JOURNAL OF MEDICINAL CHEMISTRY, 59 (5). pp. 2067-2082. ISSN 0022-2623, 1520-4804

Schindler, Lisa and Bernhardt, Guenther and Keller, Max (2019) Modifications at Arg and Ile Give Neurotensin(8-13) Derivatives with High Stability and Retained NTS1 Receptor Affinity. ACS MEDICINAL CHEMISTRY LETTERS, 10 (6). pp. 960-965. ISSN 1948-5875

Schweizer, Daniel and Schoenhammer, Karin and Jahn, Michael and Goepferich, Achim (2013) Protein-Polyanion Interactions for the Controlled Release of Monoclonal Antibodies. BIOMACROMOLECULES, 14 (1). pp. 75-83. ISSN 1525-7797, 1526-4602

Sellmer, Andreas and Stangl, Hubert and Beyer, Mandy and Gruenstein, Elisabeth and Leonhardt, Michel and Pongratz, Herwig and Eichhorn, Emerich and Elz, Sigurd and Striegl, Birgit and Jenei-Lanzl, Zsuzsa and Dove, Stefan and Straub, Rainer H. and Kraemer, Oliver H. and Mahboobi, Siavosh (2018) Marbostat-100 Defines a New Class of Potent and Selective Antiinflammatory and Antirheumatic Histone Deacetylase 6 Inhibitors. JOURNAL OF MEDICINAL CHEMISTRY, 61 (8). pp. 3454-3477. ISSN 0022-2623, 1520-4804

She, Xueke and Pegoli, Andrea and Mayr, Judith and Huebner, Harald and Bernhardt, Guenther and Gmeiner, Peter and Keller, Max (2017) Heterodimerization of Dibenzodiazepinone-Type Muscarinic Acetylcholine Receptor Ligands Leads to Increased M2R Affinity and Selectivity. ACS OMEGA, 2 (10). pp. 6741-6754. ISSN 2470-1343

Spinnler, Katrin and von Kruechten, Lara and Konieczny, Adam and Schindler, Lisa and Bernhardt, Guenther and Keller, Max (2020) An Alkyne-functionalized Arginine for Solid-Phase Synthesis Enabling "Bioorthogonal" Peptide Conjugation. ACS MEDICINAL CHEMISTRY LETTERS, 11 (3). pp. 334-339. ISSN 1948-5875

Szczepanska, Katarzyna and Karcz, Tadeusz and Dichiara, Maria and Mogilski, Szczepan and Kalinowska-Tluscik, Justyna and Pilarski, Boguslaw and Leniak, Arkadiusz and Pietrus, Wojciech and Podlewska, Sabina and Popiolek-Barczyk, Katarzyna and Humphrys, Laura J. and Ruiz-Cantero, M. Carmen and Reiner-Link, David and Leitzbach, Luisa and Lazewska, Dorota and Pockes, Steffen and Gorka, Michal and Zmyslowski, Adam and Calmels, Thierry and Cobos, Enrique J. and Marrazzo, Agostino and Stark, Holger and Bojarski, Andrzej J. and Amata, Emanuele and Kiec-Kononowicz, Katarzyna (2023) Dual Piperidine-Based Histamine H₃ and Sigma-1 Receptor Ligands in the Treatment of Nociceptive and Neuropathic Pain. JOURNAL OF MEDICINAL CHEMISTRY, 66 (14). pp. 9658-9683. ISSN 0022-2623, 1520-4804

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Tropmann, Katharina and Hoering, Carina and Plank, Nicole and Pockes, Steffen (2020) Discovery of a G Protein-Biased Radioligand for the Histamine H-2 Receptor with Reversible Binding Properties. JOURNAL OF MEDICINAL CHEMISTRY, 63 (21). pp. 13090-13102. ISSN 0022-2623, 1520-4804

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Wuertenberger, Irene and Angerrnaier, Bernhard and Kircher, Brigitte and Gust, Ronald (2013) Synthesis and In Vitro Pharmacological Behavior of Platinum(II) Complexes Containing 1,2-Diamino-1-(4-fluorophenyl)-2-alkanol Ligands. JOURNAL OF MEDICINAL CHEMISTRY, 56 (20). pp. 7951-7964. ISSN 0022-2623, 1520-4804