The Two-Minute Walk Test in Persons with Multiple Sclerosis: Correlations of Cadence with Free-Living Walking Do Not Support Ecological Validity

Karle, Viktoria and Hartung, Verena and Ivanovska, Keti and Maeurer, Mathias and Flachenecker, Peter and Pfeifer, Klaus and Tallner, Alexander (2020) The Two-Minute Walk Test in Persons with Multiple Sclerosis: Correlations of Cadence with Free-Living Walking Do Not Support Ecological Validity. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 17 (23): 9044. ISSN , 1660-4601

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Abstract

The two-minute walk test (2MWT) is a frequently used walking capacity test in persons with multiple sclerosis (pwMS). However, less is known about its relevance with regards to walking capacity during free-living walking performance. Therefore, the ecological validity of the 2MWT was tested by 1. computing free-living minutes with the same intensity (cadence) as during the 2MWT and 2. investigating the relationship between 2MWT cadence and minutes with the same cadence during free-living walking. 20 pwMS aged 44.2 +/- 12.2 (Expanded Disability Status Scale (EDSS) score of 3.1 +/- 1.4) performed a 2MWT and wore an accelerometer for seven days. The number of pwMS reaching 100%, 90%, 80% or 70% of 2MWT cadence for at least one minute a day and minutes/day with at least 100%, 90%, 80% and 70% of 2MWT cadence during free-living walking was calculated. Six participants reached 100% of the 2MWT cadence for at least one minute/day during free-living walking. A total of 80% 2MWT cadence was the first intensity category that was reached by all participants during free-living walking. No significant correlation was found between cadence in the 2MWT and minutes in which this cadence was reached during free-living walking. Ecological validity with regard to walking intensity could not be confirmed in our study sample.

Item Type: Article
Uncontrolled Keywords: PHYSICAL-ACTIVITY; 6-MINUTE WALK; ACCELEROMETRY; AMBULATION; INTENSITY; CAPACITY; GAIT; multiple sclerosis; two-minute walk test; ecological validity; habitual walking; free-living walking; walking performance; accelerometry
Subjects: 300 Social sciences > 370 Education
Divisions: Human Sciences > Institut für Erziehungswissenschaften
Depositing User: Dr. Gernot Deinzer
Date Deposited: 05 Mar 2021 09:56
Last Modified: 05 Mar 2021 09:56
URI: https://pred.uni-regensburg.de/id/eprint/43231

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